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Leber’s hereditary optic neuropathy: from lab to clinic
Leber’s hereditary optic neuropathy (LHON) was the first clinically described mitochondrial disorder (1871). This article reviews the pathophysiology and clinical features of LHON with a focus on translational research. G11778A is currently the most common mutation worldwide and is associated...African-Caribbean ethnicity key risk factor for sight-threatening diabetic eye disease
People of African-Caribbean ethnicity with Type 2 diabetes are a third more likely to develop a condition called sight-threatening diabetic retinopathy (STDR) than other ethnic groups, according to researchers from King’s College London. The study, published in the journal Diabetes...How to pass the FRCOphth Part 1 as a foundation trainee: some practical tips
Attempting the FRCOphth Part 1 examination as a foundation trainee requires significant time and financial commitment. Unlike the MRCP and MRCS examinations, the curriculum of this exam does not overlap with the undergraduate syllabus. As such, it is a steep...The miracle of multi-professional working in modern-day eyecare
"It’s a Tuesday morning, and I’m in the presence of one of the most mind-boggling accomplishments in human history. This thing is so astounding in its complexity and scope, it makes the Panama Canal look like a third grader’s craft...The restorative prescription: The case for carbon-negative healthcare
The Hippocratic Oath begins with a simple, profound directive: ‘First, do no harm.’ Yet, for decades, the global healthcare sector has been locked in a quiet paradox. While doctors work tirelessly to treat illnesses, heat exhaustion and vector-borne diseases, the...Meltdown, Spectre, Flying Hospitals and Spy Cams
iPhone slowdown In early 2018 users discovered that Apple was slowing down older iPhones intentionally. The reported reason was to prolong the usable battery life. These changes were made without the knowledge or consent of owners. Unsurprisingly, a community backlash...
Safe cataract extraction with underlying hypotonous cilio-choroidal detachment following trabeculectomy surgery
The authors of this study (including the reviewer of this article) describe a surgical technique for phacoemulsification in the presence of shallow choroidal detachment owing to hypotony following trabeculectomy. In their case series, four eyes of four patients with advanced...
