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Ocular manifestation of Marfan Syndrome
This repeated cross-sectional study collected data in 2003-2004 and 2014-2015 to investigate changes in ocular features in Marfan syndrome (MFS) fulfilling the Ghent-2 criteria. Ghent-2 is a set of criteria by which MFS are identified and includes aortic root aneurysm...
Recognising clinical characteristics of blepharospasm
Focal dystonia is regarded as a characteristic feature of blepharospasm, but patients do not always present with these motor symptoms. The authors present a retrospective analysis of data from a large number of patients treated for drug-induced or essential blepharospasm...
Paraneoplastic optic neuropathy features
This is a retrospective review of seven patients diagnosed with paraneoplastic optic neuropathy (PON) between January 2015 and June 2017. Five patients had a history of primary malignancy, including papillary thyroid carcinoma, type B thymoma, testicular seminoma and lung carcinoma....
Acetazolamide and CMO
The authors set out to analyse the effect of acetazolamide therapy on inflammatory cystoid macular oedema (CMO) as defined by change in central macular subfield thickness (CST), as well as its effect on visual acuity. A retrospective chart review was...
Radiotherapy for orbital apex cavernous haemangiomas
This is a review of six patients with cavernous venous malformations (haemangiomas) involving the orbital apex who were treated with fractionated stereotactic radiotherapy. Patients were diagnosed on MRI imaging with only one having had previous surgery to debulk the lesion....
Colour Doppler imaging before and after orbital decompression in thyroid eye disease
In this prospective, uncontrolled study euthyroid patients with moderate to severe inactive thyroid eye disease underwent colour Doppler imaging before and after orbital decompression. Patients with dysthyroid optic neuropathy, corneal breakdown, systemic disease (diabetes, cerebrovascular accident, cardiovascular and peripheral vascular...
Surgical results in spinocerebellar ataxia (SCA)
Patients with SCA frequently develop ocular motility abnormalities including nystagmus, abnormal smooth pursuits, dysmetric saccades, divergence paresis and ophthalmoplegia. Incidence of diplopia is higher in SCA type 3. The purpose of this study was to evaluate surgical responses and outcomes...
Switchover study from Botox to Xeomin for facial dystonia
This study carried out in the UK compared the clinical effectiveness and efficiency of switching patients from Botox® injections to Xeomin®. This was carried out in 20 essential blepharospasm, 12 hemifacial spasm and six aberrant facial nerve regeneration patients. Patients...
LACTOSE control score for exotropia
The purpose of this study was to determine the extent of change in control over multiple measurements in a single clinic visit using the Look and Cover, then Ten seconds of Observation Scale for Exotropia (LACTOSE) scoring system in patients...
Migraine and risk of retinal artery occlusion
This retrospective cohort study assessed whether migraine was associated with an increased risk of retinal artery occlusion. They reviewed a large insurance database of 418,965 patients who suffered with migraines between 2007 and 2016. These were then matched with an...
Ocular toxoplasmosis
This is a retrospective study of 106 patients between March 2011 and June 2018, of 37 IgM + group and 69 IgM - group of patients. The clinical features, demographics of patients with ocular toxoplasmosis (OT) were studied according to...
