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The creation of PlayDoh^® models as an educational tool for teaching anatomy of the eyelid

An understanding of the anatomy of the eyelid is essential for training in oculoplastic surgery. Active learning has been shown to increase knowledge and retention and has an advantage over passive teaching methods alone [1,2]. PlayDoh® models have been used...

Gene therapy for inherited retinal disease: the Manchester Ocular Gene Therapy Group MDT service

The authors describe the process set up in Manchester for the optimum delivery and assessment of a new gene therapy treatment for patients with RPE65 IRD. Inherited retinal dystrophies (IRDs) are the second commonest cause of severe visual impairment in...

Safety and efficacy of a nurse-led intravitreal injection service using an Precivia® injection assist device

Nurse-led intravitreal injections have become of great importance for busy eye units. In this article, the authors present safety data from five years of a nurse-led service with the use of the Precivia® intravitreal injection assist device. Intravitreal injections of...

FAQs about cerebral visual impairment (CVI): identifying and helping those affected

Cerebral visual impairment is common in both adults and children, yet the diagnosis can easily be missed unless one is tuned into the presenting features. This article provides a succinct introduction to this important topic. What is vision? Vision is...

Retinoblastoma – the challenges of a rare cancer and the role of international partnerships

Introduction: the global challenge The global burden of retinoblastoma (Rb) is one in 15,000-18,000 live births, which equates to 8000 new cases worldwide each year. The global disparities in Rb outcome represent a paradigm of health inequality worldwide [1]. In...

General purpose AI: Transitioning from high performance in highly curated settings to useful applications in ophthalmology

Artificial intelligence (AI) may be understood as the ability of machines to perform tasks which otherwise require human perception, reasoning, or learning. With the advent of deep learning, AI has achieved remarkable results across a wide range of medical tasks...

‘Phaco-plus’ procedures at forefront of modern glaucoma management

Glaucoma and cataract increasingly present as a ‘two-in-one’ surgical opportunity. In the UK, new modelling suggests ~1 million adults aged ≥40 may currently have glaucoma, with a projected rise to ~1.6 million by 2060 as the population ages and demographics...

Emerging developments in dry eye

An estimated 344 million people worldwide suffer from dry eye [1]. This chronic syndrome is characterised by a vicious cycle of tear film hyperosmolarity, tear instability and corneal stress, leading to increased friction, inflammation, ocular surface damage and decreased visual...

An update on inherited retinal disorders (part 2): Approaches to therapy for IRDs

Part 1 of this topic can be found here There are currently no proven cures for inherited retinal disease (IRD). However, multiple avenues of research are being investigated to better understand disease mechanisms and trial potential therapies that may slow...

Genetic profiling for personalised healthcare solutions in AMD – an update

Age-related macular degeneration (AMD) is a multifactorial condition influenced by genetics and lifestyle factors (Table 1). This article outlines several recent advances in AMD genetics, as well as evolving therapeutic concepts and established practical measures for the treatment and /...

Sharing best practice and landmark evidence in glaucoma care

Evolving technology, best practice and landmark evidence in glaucoma care were reviewed by an international expert faculty in session presentations and debates during the 11th Moorfields International Glaucoma Symposium 2019. The authors were meeting chairs and provide an overview of...