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2552 results found

Choroidal defects in neurofibromatosis

The aim of this study was to investigate the frequency of choroidal abnormalities using infrared reflectance imaging with optical coherence tomography (OCT) in paediatric patients with neurofibromatosis (NF) type 1. Thirty-eight eyes of 19 patients were reviewed. NF1 was diagnosed...

Nystagmus and associated diagnosis

Patients with nystagmus attending a Low Vision clinic in Sweden were included in this study. Medical records were reviewed to exclude those with general diagnoses that could explain the nystagmus. The remaining group of patients underwent subjective refraction, retinoscopy, ocular...

Resolution of mid-peripheral schisis in x-linked retinoschisis with the use of dorzolamide

X-linked retinoschisis (XLRS) is an early onset hereditary retinal dystrophy. It is caused by mutations of the RS1 gene. Common manifestations of XLRS are schitic lesions at the macula, as well as infero-temporal schisis. Carbonic anhydrase inhibitors have previously been...

Avastin vs. Volon A for diabetic macular oedema

This prospective randomised interventional clinical trial compared 30 diabetic patients with macular oedema treated with either intravitreal injections of bevacizumab (Avastin) or triamcinolone (Volon A). One group initially received three injections of 2.5 mg Avastin in monthly intervals whilst the...

Microperimetry of subretinal drusenoid deposits

Subretinal drusenoid deposits (SDD), originally termed ‘reticular pseudo-drusen’, have recently been identified by histology and optical coherence tomography (OCT) as aggregations located in the subretinal rather than the sub retinal pigment epithelium (RPE) space. These deposits affect the amount of...

Macular oedema after cataract surgery in diabetic patients

The authors describe a multi-centre prospective observational study of 293 participants that underwent cataract surgery who all had diabetic retinopathy without definite central-involved macular oedema. Forty-five clinical sites took part throughout the United States. Patients were eligible if there was...

Risk factors and untreated POAG

The authors examined 50 untreated open angle glaucoma patients to determine if there was an association between the level of glaucomatous damage and documented risk factors. In this study the authors measured the extent of morphologic and functional glaucomatous damage...

Two illustrative cases of AZOOR

The authors present two illustrative cases of acute zonal occult outer retinopathy (AZOOR) which causes acute idiopathic blind spot enlargement. The disease is characterised by sudden loss of outer retinal function associated with photopsia, with minimal or no fundoscopic changes...

Diclofenac versus Bromfenac after cataract surgery

Non-steroidal anti-inflammatory drugs (NSAIDs) are commonly used after cataract surgery to reduce inflammation and cystoid macular oedema (CMO). Diclofenac 0.1% is used three to five times daily for 28 days and Bromfenac 0.09% twice daily for 14 days postoperatively. The...

Glaucoma and capillary perfusion

Elevated IOP is important but not the sole factor responsible for retinal ganglion cell (RGC) death and optic nerve damage in glaucoma. There is increasing evidence that visual loss correlates with macular inner retinal thinning. A total of 148 eyes...

OCT in microtropia

The aim of this study was to assess whether OCT could be useful in detecting and documenting fixation in children with microtropia. The study used spectral domain OCT (Cirrus) in 15 patients (10 female, five male) and 10 control eyes....

OCT-A imaging in Grave’s orbitopathy and orbital decompression

In this case series of 12 patients and 24 orbits, the authors describe the changes in the optic nerve and peripapillary blood vessel density in patients with moderate to severe Grave’s Orbitopathy (GO) undergoing orbital decompression. The patients undergoing orbital...