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Genetic therapy gives infants life-changing improvements in sight

Four young children have gained life-changing improvements in sight following treatment with a pioneering new genetic medicine through Moorfields Eye Hospital and UCL Institute of Ophthalmology, with the support of MeiraGTx. The children were born with a severe impairment to...

A European ophthalmology perspective

Europe: from the Greek eurus: broad, wide, and ops: eye, face, sight. Thus Europe = the far-sighted (lady). For my first contribution to this column – as the successor of Jonathan Park, whose witty observations and entertaining style many of...

The visual field of empathy: What ophthalmology taught me about seeing the patient

It was a busy shift on the ward. Amongst the chest pains and fevers was an older woman referred for confusion. She was quiet, polite, and compliant – the kind of patient who doesn’t raise alarms. As we spoke, I...

Ophthalmology in ancient india, Sushruta’s time and the modern era

While reading an article related to the history of Indian ophthalmology, I came across this description of a surgical procedure: “The doctor warmed the patient’s eye with the breath of his mouth. He rubbed the closed eye of the patient...

Blind Faith: In Conversation with Mariya Moosajee

In light of the BBC releasing Blind Faith: Do genetic eye disease ‘treatments' work? earlier this year, a documentary which follows BBC journalist Ramadan Younes as he investigates practitioners who falsely claim to have ‘treatments’ for genetic eye disease, Eye...

The fragile p-value

Abdus Samad Ansari explores the limitation of the p-value and the application of the fragility index in clinical trials. Clinical trials and tribulations? The restoration of vision or more purely the gift of sight is an aspect of care that...

Redeployment during the COVID-19 pandemic: personal accounts from four ophthalmology trainees

We once believed that the coronavirus would not penetrate the safe confines of the United Kingdom, like so many outbreaks before this. Once the news came that this pandemic descended into our hospitals, the anxieties about redeployment began. Many of...

Planes, trams, and auditoriums: Beware predatory conferencing

Predatory open-access journals and predatory conferences are considered the two main areas of predatory infiltration in academic medicine that are of growing concern [1–7]. Unsolicited publishing requests from potentially predatory publishers occur frequently among faculty in ophthalmology [8]. Predatory conferencing...

Ophthalmology in the developing world

After the second year of medical school, I spent my summer vacation working as a volunteer for a small Italian non-government organisation (NGO), named HEALTH-AID. As part of my volunteering experience, I joined a team of European doctors, medical students...

Bosch-Boonstro-Schaaff optic atrophy syndrome (BBSOAS) NR2F1 mutation

An experienced ophthalmologist can make an anatomical diagnosis of childhood visual impairment based upon the surgical sieve, i.e., congenital and acquired. But an ophthalmologist cannot work in isolation to make an aetiological diagnosis – one would require the help of...

Can thou lyse this? A national study of emergency canthotomy and cantholysis

Eighty-two-year old Janet Smith woke up on the floor. Had she been unconscious? Her head hurt. It was the middle of the night, but in the darkness she suddenly wasn’t sure whether she could see out of her right eye....

Is it worth performing cataract surgery in amblyopic eyes?

It was estimated that about 3% of all cataract surgeries in adults were performed in eyes that have pre-existing amblyopia, and there is a long-standing belief that eyes with amblyopia have limited benefit from cataract extraction in the adult age....