You searched for "retinal"
Gender and ethnicity related differences in optic nerve head
The authors investigated the effect of ethnicity and gender on optic nerve head morphology comparing Indian and Caucasian males and females. The optic nerve head was investigated using spectral-domain optic coherence tomography (SD-OCT). Results showed that disc and rim areas...
Congenital aniridia clinical features
In this study the authors investigated the various ocular and systemic features associated with congenital aniridia in Indian eyes (262 eyes of 131 patients). The median age at time of first hospital visit was eight years (one day to 73...
MicroRNA mediate retinoblastoma signal transduction
MicroRNAs (miR) are small non-coding single-stranded RNA molecules, normally 22 nucleotides long. There is a large family of miR that control protein expression by binding to mRNAs, leading to their degradation. One important role of miR is in tumours where...
An atypical presentation of Vogt-Koyanagi-Harada Disease
The authors present a single case of atypical presentation of Vogt-Koyanagi-Harada disease. A 42-year-old female presented with unilateral visual loss associated with systemic symptoms of fever and headache. Initial ophthalmic examination revealed a unilateral neuroretinitis, however, investigations for infectious and...
Ocular characteristics in Marfan syndrome
Marfan syndrome (MFS) is a genetic disorder with clinical manifestations associated with cardiovascular, ocular and skeletal organ systems. Typical signs are descending aortic root aneurysms, ectopia lentis, tall stature and scoliosis. This observational study looked at the ocular characteristics, visual...
Translucent vs. lightproof occluders
This study investigates the change in visual acuity following occlusion in amblyopes and non-amblyopes using translucent versus lightproof occlusion of the dominant eye. Group 1 non-amblyopes consisted of 26 subjects: 16 visually normal and 10 strabismic or anisometropic subjects without...
HtrA1 enhances cell senescence
A genetic basis for age-related macular degeneration (AMD) has been greatly advanced in recent years. The role of identified pathways such as complement factor H in AMD has been widely investigated. However, the effect of other gene variants identified by...
Nanoparticle administration of latanoprost
Glaucoma is a progressive optic neuropathy characterised by increased ocular pressure and loss of retinal ganglion cells. Conventional drug therapy with eye drops to reduce intraocular pressure (IOP) has variable bioavailability and can lead to ocular surface disease. In this...
Oral proton pump inhibitors in macular degeneration patients
The authors report five patients with advanced wet macular degeneration and poor vision with onset or enhancement of visual hallucinations with the use of proton pump inhibitors for heartburn management. The hallucinations were reversible with discontinuation of medication. The authors...
Radiation maculopathy
This is a retrospective non-randomised study of 13 consecutive eyes of 13 patients affected by radiation maculopathy secondary to eye irradiation for primary uveal melanoma (Iodine-125 brachytherapy). All patients were treated with a single intravitreal 0.7mg dexamethasone implant and full...
Is myopia protective against progression of diabetic retinopathy?
This population-based cohort study assessed the association of refractive error with the incidence and progression of diabetic retinopathy (DR); 1562 eyes of 860 patients with diabetes and gradable retinal photographs were included. Baseline data was taken between 2004-2009 and follow-up...
