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Yolk sac tumours of the orbit and sinonasal tract

This paper outlines two case reports of patients with yolk sac tumours (YSTs) and carries out a review of the literature on this rare malignancy. YSTs are a type of germ cell tumour and primarily occur in the gonads. Ten...

Proof of concept for using aqueous humour to detect retinoblastoma variant

A proof of concept study is presented with the aim of assessing the feasibility of using aqueous humour surrogate marker for tumour tissue for identifying retinoblastoma RB1 variant. Three children undergoing enucleation for retinoblastoma were recruited from a single centre....

Visual acuity outcomes after cataract surgery in type 2 diabetes (NIDDM): the action to control cardiovascular risk in diabetes (ACCORD) study

This is a retrospective case-control study of 1136 eyes enrolled in the 784 ACCORD patients receiving cataract surgery between 2001-2014. 362 / 1136 eyes had gradable fundus photography for diabetic retinopathy (DR). Seven hundred and sixty-two eyes (67.1%) achieved 20...

Macular measurements for amblyopic eyes

This study aimed to evaluate the macular parameters including foveal avascular zone (FAV) size and vessel density in amblyopia vs fellow eyes. The study included 23 unilateral amblyopia children (9.86 ±3.12 years; 52.2% female) and non-amblyopia control eyes (8.67 ±2.06...

Should we be looking for anemia in the presence of papilloedema?

The authors present a retrospective case notes review of patients diagnosed with idiopathic intracranial hypertension (IIH) presenting to a tertiary neuro-ophthalmology clinic over a 32-month period. The IIH group were age and sex matched with other patients attending the clinic...

Does methanol poisoning require ophthalmic investigation?

The authors report a case series of 21 patients (41 eyes) diagnosed with acute methanol poisoning following an outbreak in Tunisia in 2020. All patients underwent a complete ophthalmological examination including visual fields, colour vision test and optical coherence tomography...

Clinical predictors of proliferative sickle cell retinopathy

Sickle Cell Disease (SCD) is an inherited disorder resulting in production of Haemoglobin S (HbS), which aggregates in conditions of hypoxia, acidosis or hyperosmolarity. This leads to vascular stasis, thrombosis and ischaemia. The authors present a cross-sectional study (45 consecutive...

MPH treatment effect in ADHD on choroidal vascular index

In this study the authors aimed to investigate the choroidal vascular index (CVI) in treatment-free children with ADHD, children regularly taking methylphenidate (MPH) and healthy controls. This was a prospective cross-sectional study of 52 patients with newly diagnosed ADHD, 46...

PAX6 methylation and myopia

The authors present a case control study of 41 adolescents (age 12–14) with myopia and 39 age- and sex-matched non-myopic controls. The myopic patients were sub-divided into mild, moderate and severe myopia subgroups. DNA was extracted from peripheral blood samples...

Macular choroidal changes after inferior oblique muscle surgery

This study was undertaken to investigate the retinal neurovasculature, choroidal thickness and choroidal vascular index (CVI) changes at the macula at one week, one- and three-month intervals post inferior oblique muscle myectomy. The hypothesis was that, given the close proximity...