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Volunteer abroad: the Khmer Sight Foundation

A team of volunteers describe their experiences of working with the Khmer Sight Foundation in Cambodia. Cambodia has a population of 15 million people, of whom an estimated 300,000 are blind. This figure is increasing by 10,000 each year. Three-quarters...

Effects of ML4 on the eye

Mucolipidosis type IV (ML4) is an autosomal recessive lysosomal storage disease and is caused by variants of the MC0LN1 gene. It often presents in young individuals with eye and ocular adnexa issues. The authors present a case report and literature...

The next wave of AI in ophthalmology: From screening to communication

Artificial intelligence (AI) is reshaping ophthalmology, moving from research laboratories into everyday clinical care [1]. With its strong reliance on imaging and pattern recognition, ophthalmology is uniquely positioned to benefit from AI innovations. These developments range from autonomous disease screening...

How to achieve 1% solution of Lissamine green

Lissamine green (LG) concentration of 1% is clinically effective in the diagnosis of ocular surface disease. LG is now commercially available only in a form of dye-impregnated strips, whose concentration is insufficient. This study examined how to achieve 1% concentration...

VEGF and axial length (RVU)

The authors of this paper set out to examine whether the concentrations of VEGF in the vitreous were associated with refractive error and axial length in eyes without retinal disease, except of macular holes or epiretinal membranes. A vitreous sample...

Moorfields earns UK’s first UKAS accreditation for ophthalmic and vision science (IQIPS)

The United Kingdom Accreditation Service (UKAS) has granted the first accreditation for Ophthalmic and Vision Science to Moorfields Eye Hospital. The award was made to the Electrophysiology Department at Moorfields under the Improving Quality In Physical Services (IQIPS) programme.

Pathophysiology of diabetic macular oedema: why combination therapy may be better

The prevalence of diabetes has continued to increase over the years. It is currently estimated that there are 382 million with diabetes worldwide in 2013, and that this figure is expected to rise to 592 million by 2035 [1]. In...

Digital eyecare – enabling better communication between primary and secondary care

Alexander Chiu and his co-authors highlight innovations influencing healthcare advancement and how trainees can get involved. Hospital eye services (HES) were under great pressure to meet demand, even before the COVID-19 pandemic. This pressure has increased with the cancellation and...

Global health milestone as Pakistan becomes 19th country to eliminate blinding trachoma

Sightsavers commends Pakistan following the World Health Organization (WHO) announcement that it has become the nineteenth country to eliminate blinding trachoma as a public health problem. This phenomenal achievement means around 3.7 million people [1] in Pakistan are no longer...

Enhancing glaucoma awareness and management in Nigeria – from grass roots to national policy development

This is the second in a series (see Part 1 here) of three articles about strengthening eye health services in Nigeria through collaboration with the LINKS and Networks run at the International Centre for Eye Health, LSHTM. This article highlights...

Effective management of dry eye and ocular surface disease

Experts recommend a consistent approach to diagnosis, therapeutic targeting by disease subtype and escalation of therapy when tear substitutes are not sufficient. Experts call for a consistent, unified approach to diagnosis of dry eye disease (DED), with a new simple...

Retinoblastoma chemotherapeutic drugs and their toxic effects on RPE cells

There is reported clinical evidence of retinal pigment epithelium (RPE) alterations after intra-arterial (IAC) and intravitreal chemotherapy (IViC) of retinoblastoma. The purpose of this study was to investigate the cellular toxic effects of melphalan, topotecan and carboplatin on the RPE...