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Belfast briefing: Retina Day roundup from the RCOphth 2024 Annual Congress
2 August 2024
| Rod McNeil
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EYE - General
Belfast hosted this year’s Royal College of Ophthalmologists’ (RCOphth) Annual Congress, a meeting dedicated to sharing advances, knowledge and clinical practice points in ophthalmic care. This article summarises selected talks by medical and surgical retina specialists during the Retina Subspecialty...
Control of diabetic retinopathy after bariatric surgery
3 June 2021
| Tasmin Berman
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EYE - Vitreo-Retinal
This systemic review and meta-analysis assessed prevalence of diabetic retinopathy including sight-threatening diabetic retinopathy after surgery. They included 14 studies with 110,300 surgical patients and 252,289 control subjects. They proposed that the risk of having any form of diabetic retinopathy...
What’s next in retinal imaging? Faster, deeper and full-on
Fast-evolving technological leaps are opening the way toward clinically useful ocular coherence angiography, generating 3-dimensional microvasculature maps without intravenous dye injection, as well as whole-eye imaging, handheld patient-operated optical coherence tomography (OCT) devices and, for challenging vitreoretinal procedures, integrated intraoperative...Renewed momentum in ocular gene and cell therapy, broadening application to chronic disease
Gene and cell therapies offer the prospect of ground-breaking new avenues for the treatment of diseases, reflected in a renewed explosion of interest and investment in retinal gene therapy. Rod McNeil reports recent clinical trial readouts across a diverse range...Best way to detect glaucoma progression: by reflecting on the past 25 years
1 June 2018
| Leon Au, Cecilia Fenerty
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EYE - Glaucoma
Glaucoma – a condition of optic neuropathy leading to progressive visual field loss often associated with raised intraocular pressure. It is fair to say that our definition for this condition has remained unchanged over the last 25 years and the...
Relationship between diabetic retinopathy and cerebrovascular reactivity changes
1 March 2024
| Claire Howard
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EYE - Neuro-ophthalmology
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Cerebral vasomotor reactivity, breath-holding index, diabetes mellitus, diabetic retinopathy, transcranial Doppler ultrasound
Cerebral micro-angiopathy caused by diabetes can manifest itself as an impairment in cerebrovascular reactivity. Transcranial doppler ultrasound (TCD) is a cost-effective and non-invasive way to measure the cerebrovascular reactivity. This study aimed to assess the relationship between the grade of...
Sickle cell eye disease: an overview of vitreoretinal complications and their surgical management
1 December 2016
| Antonio Berarducci, Tom Williamson
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EYE - Vitreo-Retinal
Sickle cell disease is the most common genetic disorder worldwide and is associated with lifelong anaemia, intermittent pain and multi-organ morbidity. Ocular involvement can be associated with significant visual impairment due to the complications of proliferative sickle retinopathy (PSR). Occasionally...
Effect of voriconazole of vision of healthy volunteers
1 December 2014
| Bheemanagouda Patil
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EYE - Vitreo-Retinal
Voriconazole is a broad spectrum, triazole antifungal agent used for systemic fungal infections. It has a favourable safety profile and is available in both intravenous and oral forms. The commonest adverse drug reactions with voriconazole are changes in visual perception,...
Association of pendular waveform and retinal disorders
4 August 2021
| Fiona Rowe (Prof)
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EYE - Paediatrics, EYE - Strabismus
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Nystagmus, nystagmus waveform, retina disorders
The authors aimed to evaluate the relationship between retinal disorders and pendular low amplitude high frequency components (PLAHF) waveform by collecting nystagmus eye movement recordings, electroretinography (ERG) and gene tests. Retinal disorders were diagnosed by clinical phenotype and genotype characteristics....
Normal reference values for the RETeval device
The purpose of this study was to provide normative data of full-field electroretinography (ERG) responses in the paediatric population using the RETeval device in healthy children with normal retinas. This was a prospective study of 38 eyes of 20 patients...Evaluation of fluocinolone acetonide in the management of BRC
1 June 2022
| Jonathan Chan
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EYE - Vitreo-Retinal
This is a single-centre, retrospective, intervention study of 15 eyes of birdshot retinochoroiditis (BRC) patients who received Iluvein, with a mean follow-up period of 31 months. Five eyes had previously received dexamethasone intravitreal implant 0.7mg (Ozurdex). Fluorescein angiography (FA) showed...
Correlation between aqueous flare and macular microvascular status in diabetes mellitus
7 April 2021
| Sofia Rokerya
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EYE - Vitreo-Retinal
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Aqueous flare, Diabetic retinopathy, Inflammation, Laser flare-cell meter, Microvascular injury, Optic coherence tomography angiography
The authors report a cross-sectional study which was conducted to investigate the correlation between aqueous flare and macular microvascular status, assessed by optic coherence tomography angiography (OCTA) in diabetes mellitus. Fifty-two diabetic patients with non-proliferative retinopathy, 44 diabetic patients without...