You searched for "metastatic"
Periocular sweat gland carcinomas
This is an interesting review of a rare group of tumours which together comprise the adnexal sweat gland carcinomas. Although there are only 22 patients, this is the largest cohort ever published. The authors summarise the clinical presentation, stage, management...
Results of changed treatment for retinoblastoma
Systemic chemotherapy was adopted in Kobe in 1996. In this study the authors analyse the clinical manifestations and results of treatment for patients with retinoblastoma since then. This review is of 43 eyes of 34 patients. Those with follow-up to...
Diagnosis and management of solitary fibrous tumour
This is a retrospective review of 21 patients diagnosed with solitary fibrous tumour of the orbit between 1996 and 2018 at a single centre. The authors reviewed the clinical presentation, management and course of the disease and reanalysed the histopathology...
Differentiating orbital tumours on MRI
This is a literature review examining the ability of specific MRI modalities to differentiate between benign and malignant tumours of the orbit. The authors identified 29 articles reporting diffusion weighted image (DWI) values and corresponding apparent diffusion coefficients (ADC) for...
Endophthalmitis after intravitreal anti-VEGF injection
The authors report the results of a retrospective multicentre study conducted at 17 retina referral centres to investigate the microbial spectrum of endophthalmitis after anti-VEGF injections. A total of 83 cases of culture-positive endophthalmitis (58.4%) were included. The most frequent...An eye on novel anti-cancer agents: an evidence-based approach to external eye assessment
Novel anti-cancer therapies have led to significant advancement in cancer treatment, however, they can be associated with external eye complications. It is important to be mindful of such adverse effects during assessment of patients enrolled in clinical trials. Annually, approximately...Retinoblastoma – the challenges of a rare cancer and the role of international partnerships
Introduction: the global challenge The global burden of retinoblastoma (Rb) is one in 15,000-18,000 live births, which equates to 8000 new cases worldwide each year. The global disparities in Rb outcome represent a paradigm of health inequality worldwide [1]. In...Understanding and confronting bacterial endophthalmitis
Abdus Samad Ansari highlights the importance of early recognition of this condition using an unusual presentation. Endophthalmitis is a medical emergency with devastating consequences. Despite adequate treatment, severe cases frequently result in permanent blindness. Endophthalmitis involves inflammation of both the...A case of bilateral idiopathic sclerochoroidal calcification
Idiopathic sclerochoroidal calcification (ISC) is a rare, benign disorder of the choroid and sclera. We present a visually asymptomatic 83-year-old caucasian male with clinical findings bilaterally of ISC, and discuss the investigations required to confirm diagnosis and help prevent further...Retinoblastoma management update (part 1): clinical features, diagnosis and genetics
The first of a two part series, this article will discuss the clinical features, diagnosis and genetic aspects of retinoblastoma. Manoj Parulekar is based at Birmingham Children’s Hospital, one of the two designated national retinoblastoma and paediatric ocular oncology treatment...Retinoblastoma, CureAll and the role of global clinical, capacity strengthening and research networks
Retinoblastoma (Rb), a rare childhood eye cancer, presents a particularly compelling example of how global health partnerships can operate at the intersection of different medical disciplines, in this case: ophthalmology, oncology and public health. This article places the work of...
