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Aflibercept for the treatment of neovascular glaucoma

The aim of this study was to investigate initial results regarding the treatment of neovascular glaucoma (NVG) with intravitreal aflibercept. NVG is classified into stages 0-3. In stages 1 and 2, abnormal vessel proliferation is seen with or without elevated...

Effects of topical anaesthetic on intraocular pressure

This prospective interventional study assessed the effects of repeated intraocular pressure (IOP) using Goldmann applanation tonometry and applanation resonance tonometry in six volunteers. Previous literature supports IOP reduction using repeated applanation tonometry. Repeated IOP measures were taken alternately on 12...

Is laser refractive surgery safe for patients taking isotretinoin?

This multicentre, retrospective, interventional case series assesses the outcomes of laser in situ keratomileusis (LASIK) and photorefractive keratectomy (PRK) in 113 patients taking isotretinoin between January 2003 and September 2017. Isotretinoin is contraindicated for LASIK and PRK and patients are...

Short-term outcome after intravitreal ranibizumab injections for ROP

This is an interventional case series study of three premature babies (six eyes) with high risk prethreshold or threshold retinopathy of prematurity (ROP) with plus disease that received intravitreal ranibizumab injections for ROP. All infants received intravitreal ranibizumab injections of...

Trab360: surgical management of childhood glaucoma

This multicentre retrospective interventional case series reports the outcomes and complications of trabeculotomy ab interno using the Trab360 device in childhood glaucoma’s. Forty-six eyes of 41 patients were included and had a mean follow-up of 14.5 months. Mean preoperative intraocular...

Choroidal vascularity in NAION

The authors present a cross-sectional, non-interventional study of healthy volunteers and those with non-arteritic anterior ischaemic optic neuropathy (NAION) recruited over a six-month period at a single site. NAION is the most common cause of acute optic neuropathy over the...

Preoperative anxiety levels and pain during cataract surgery

Increased anxiety has been shown to be associated with greater pain in a number of procedures. In this observational, non-interventional study, the authors sought to evaluate the correlation between pain with phacoemulsification surgery (under topical and intracameral local anaesthesia) and...

Visual field progression after glaucoma drainage device implantation

This retrospective interventional case series assessed changes to visual fields after implantation of a glaucoma drainage device (Baerveldt, Ahmed or Molteno Devices) between 2010 and 2015. A total of 106 eyes from 96 patients were included in the final analysis...

Customised corneal crosslinking with supplemental oxygen

In this prospective interventional case series, the authors investigate using supplemental oxygen delivery during epithelium-on corneal crosslinking (CXL) with specially designed oxygen delivery goggles. Twenty-seven eyes of 24 patients underwent epi-on CXL with Riboflavin and Ultraviolet-A irradiation. At six months...

Histopathology-guided management of ocular surface squamous neoplasia (OSSN) with corneal stromal or scleral invasion using ruthenium-106 plaque brachytherapy

This is a retrospective interventional consecutive case series of 42 eyes of 42 patients with OSSN with histopathologically proven corneal stromal and / or scleral invasion following excision biopsy. The mean tumour basal diameter was 9.3mm and thickness of 3.1mm...

Outcomes following repair of early-onset versus delayed-onset rhegmatogenous retinal detachments (RD) after acute posterior vitreous detachment (PVD)

This is a retrospective single centre comparative interventional study of 210 patients in total, between 2015 to 2020, presenting with delayed RD (diagnosed >42 days after initial acute PVD presentation) compared with a 2:1 age and gender-matched acute RD cohort...

Practical Handbook for Small-Gauge Vitrectomy

The authors have set out to produce a readable, comprehensive handbook designed to instil a working knowledge in the speciality. The authors have indeed achieved their objective and created a dynamic, well-structured, stimulating book. As vitreo-retinal surgery is a rapidly...