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Clinical predictors of proliferative sickle cell retinopathy
Sickle Cell Disease (SCD) is an inherited disorder resulting in production of Haemoglobin S (HbS), which aggregates in conditions of hypoxia, acidosis or hyperosmolarity. This leads to vascular stasis, thrombosis and ischaemia. The authors present a cross-sectional study (45 consecutive...
The use of virtual reality in paediatric ophthalmology
The purpose of this study was to investigate the utility of virtual reality (VR) in the broader field of paediatric ophthalmology with review of examination, screening, diagnosis, prevention and treatment. This review also explores the potential of eye tracking used...
Nystagmus in infants (0–1 year)
This article from a tertiary hospital in Jerusalem documents the examination and investigations of 147 infants aged 0–1 years with nystagmus. The most common pathologies were albinism (59%) and inherited retinal dystrophy (IRD) (21%). They had eight patients with vertical...
Idebenone for Leber hereditary optic neuropathy
The authors present a meta-analysis of studies reporting the effects of idebenone treatment on visual acuity (VA) in patients with Leber hereditary optic neuropathy (LHON), the most common inherited mitochondrial disorder. They included randomised controlled trials, non-randomised controlled trials and...
Seeing mitochondrial disease
This review highlights mitochondrial diseases as the most common inherited neurometabolic disorders, often affecting multiple high-energy organs, with eye involvement frequently representing the earliest or predominant feature. Diagnosis is challenging due to significant genetic and clinical heterogeneity, including variable expressivity,...The future of SLT?
For Feb/Mar 2024, we are looking at a recently released laser machine to perform direct SLT – selective laser trabeculoplasty (DSLT). Although SLT is well known, DSLT is sufficiently novel that a brief description is a good place to start....
