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Orbital Schwannomas

This is a large case series of orbital Schwannomas managed at a single centre over a 26-year period. Twenty Schwannomas are reported, all but one of which was managed surgically. The tumours were all benign, had an insidious onset and...

Patterns of binocular diplopia in giant cell arteritis (GCA)

Giant cell arteritis (GCA) is a granulomatous vasculitis that targets medium and large sized vessels. Binocular diplopia has been reported in a small number of patients with visual manifestations of GCA. It can be caused by ischaemia in any segment...

The Neuro-Ophthalmology Survival Guide, 3rd Edition

Neuro-ophthalmology, a challenging ophthalmic subspecialty, demands an understanding of neuro-anatomical pathways, nuanced examination and advanced imaging. For ophthalmology trainees, foundation doctors, neurologists and emergency clinicians, it can feel daunting to frequently encounter optic neuritis, visual field defects and cranial nerve...

Two-year GATHER2 data: anatomical gains, functional questions for avacincaptad pegol in geographic atrophy

Geographic atrophy (GA) secondary to age-related macular degeneration (AMD) remains a leading cause of irreversible central vision loss, and complement dysregulation has long been implicated in its pathogenesis. In 2023, the US FDA approved the first two GA therapies, both...

Understanding amniotic membrane grafts

Safa Elhassan gives a brief review of amniotic membrane grafts and their application in theatre and clinic-based settings. Amniotic membrane (AM) transplant has been an established adjuvant treatment for many corneal, conjunctival and scleral disorders in ophthalmic clinical practice with...

Resurfacing the ocular surface

The ocular surface (OS) is an anatomical and functional unit made of the tear film, the conjunctival, limbal and corneal epithelium, the lacrimal, mucous and meibomian glands and the lids and blink reflex. The tear film is composed of a...

Treatment for cause of sudden sight loss now available through the NHS in England

The National Institute for Health and Care Excellence (NICE) has approved a treatment for Leber Hereditary Optic Neuropathy (LHON), called Idebenone (Raxone), in those aged 12 and above who are affected by the condition. LHON is a rare mitochondrial genetic...

NICE approves treatment for cause of sudden sight loss

The National Institute for Health and Care Excellence (NICE) has approved a treatment for Leber Hereditary Optic Neuropathy (LHON), called Idebenone (Raxone), in those aged 12 and above who are affected by the condition. LHON is a rare mitochondrial genetic...

Aug/Sep 2015 Quiz 2

History A two-year-old female child presented with loss of vision in her left eye. Examination showed leukocoria and intraocular calcification was identified on scanning. The suspected diagnosis was intraocular retinoblastoma and the child underwent an enucleation. The eyeball was submitted...

Corneal transplantation in the United Kingdom: are we blind to the challenges that still exist after the Organ Donation Bill?

Corneal transplantation (CT) is a significant treatment option for a huge number of patients in the United Kingdom (UK) [1]. For an individual, CT results in a substantial improvement in quality of life. Penetrating keratoplasty with full thickness grafting has...

Technique of deep corneal foreign body removal

This article has been verified for CPD. Click the button below to answer a few short questions and download a form to be included in your CPD folder. The objective is to demonstrate a method for the safe and successful...

Cataract surgery in corneal disease

Cataract surgery in the presence of corneal disease presents multiple challenges, from determining whether symptoms are lenticular or corneal in origin, to decisions regarding timing of surgery, intraocular lens (IOL) power calculation, IOL selection, surgical technique and perioperative care. Realistic...