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Building data infrastructure for eye research in the NHS: Real-world lessons from the Liverpool Eye Data Platform

The Liverpool Eye Data Platform demonstrates how governance-compliant infrastructure can bring together routinely-collected, siloed NHS eye data. Routine care delivered across the NHS generates vast amounts of clinical data within a healthcare system that is uniquely characterised by comprehensive population...

Quiz Jun/Jul 2024

History A one-year-old girl originally presented with a red eye, initially bilaterally and later in the left only. On examination a membrane was found on the tarsal conjunctiva of the upper eyelid (Figure 1). Figure 1: Anterior segment. Serum plasminogen...

What's trending Dec/Jan 2023

A round-up of the eye related hot topics that have been trending on social media over the last few weeks. #frightnight #halloween #protectyoureyes The Royal College of Optometrists advised the public against wearing novelty contact lenses this Halloween. In a...

Applying for ophthalmology ST1 in 2026: What’s new?

Competition for ophthalmology ST1 has intensified steadily over recent cycles, rising from ~9:1 (2022) to ~10:1 (2023), ~14:1 (2024) and ~22:1 (2025) [1]. Against this background, applicants benefit from a structured approach: mapping achievements to portfolio domains early, identifying gaps...

One-year result of XEN45 implant for glaucoma: efficacy, safety, and postoperative management

The authors report a retrospective, non-randomised interventional case series of 39 patients who underwent a standalone XEN45 implantation. All 39 patients (female: male=1.2: 1) completed 12-month follow-up. Mean age was 70.1 years (range 32–92). Primary outcome measures were the intraocular...

Glaucoma medications and ocular surface disease

This literature review examined ocular surface disease (OSD) associated with glaucoma medication. The authors examined the prevalence of features and management guidelines glaucoma medication associated OSD. Fifty-eight articles published within the past five years are included in this review and...

Breakthroughs in the genetics of angle-closure glaucoma

Angle closure glaucoma (ACG) is not widely known to be a familial condition, yet the recent explosion of genetic data and large scale genome wide investigations have confirmed at least 13 genetic loci associated with ACG [1], and provided some...

Management of retinal diseases: highlights from the AAO 2019 Retina Subspecialty Day Meeting

The author highlights current debate, opinion and late breaking developments in the management of retinal diseases. The American Academy of Ophthalmology’s 2019 Retina Subspecialty Day Meeting was held on 11-12 October, 2019 in San Francisco, USA. Established and emerging innovative...

Analysis of risk factors for intraocular pressure rise following insertion of fluocinolone acetonide injection in uveitic patients

For this study, the authors analysed the pooled data from three phase2b / 3 multi-centre randomised controlled trials carried out over three years. Included patients had undergone at least one of the following treatments: 1) systemic therapy (corticosteroid / immunosuppressant...

Associations with ocular surface disease in high school children

The authors aimed to determine the prevalence of ocular surface symptoms in a high school population and to evaluate its association with contact lens wear and other factors. The study had a population of 3240 students. This was a cross-sectional...

Does pregnancy cause progression of keratoconus in previously cross-linked corneas?

This is a prospective study involving 24 eyes of 19 patients with stabilised or regressed keratoconus after a successful accelerated cross linking (A-CXL) treatment. Patients were recruited at a routine follow-up visit in the first month of their pregnancy. The...

Could internuclear ophthalmoplegia aid differential diagnosis in demyelinating conditions?

The authors present a retrospective review of individuals diagnosed with either neuromyelitis optica spectrum disorder (NMOSD) or multiple sclerosis (MS). The aim of the study was to assess the prevalence of internuclear ophthalmoplegia (INO) in both groups over a 10-year...