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New mouse model of diabetes mellitus

Diabetic retinopathy (DR) is a serious complication of diabetes. It is driven by the loss of pericytes, cells which control vascular function, due to excess formation of sugar alcohols by the enzyme aldose reductase (AR). AR has been shown to...

In conversation with Dr Robert B Nussenblatt

Dr Robert B Nussenblatt is Chief of the Laboratory of Immunology at the National Eye Institute, an eminent ocular immunologist and an expert in clinical research design and conduct. Describe the success or relevance of the SUN project. The Standardization...

Haag-Streit UK to offer iTrack Advance ‘Meet the experts’ sessions at UKEGS 2024

Haag-Streit UK will be exhibiting as a gold sponsor at the United Kingdom & Eire Glaucoma Society (UKEGS) event in Southampton on the 9th and 10th October 2024, where they will be showcasing the iTrack Advance microcatheter. Delegates will have...

Topical steroids and ptosis surgery

This is a retrospective review examining the effect of prior topical steroid use on patients undergoing ptosis surgery. Out of a total of 406 eyelids undergoing ptosis repairs, 44 had received topical steroids for an average of 3.7 years prior...

Does paediatric uveitis reactivate after treatment with anti-TNF-a drugs?

As a potentially blinding disease that can affect 7-27/100000 children, uveitis remains a rare condition, where little evidence based data is available to guide management decisions. Most paediatric uveitis cases are chronic, anterior and non-infectious and may be associated with...

The last three patients: dermatology (Patient Three)

For the third and final reflection in this series (see Part 1 and Part 2), Professor Jonathan Rees recounts his experience of a patient with cancer who was failed by the NHS, and how their inadequate treatment illuminates some issues...

DMEK vs. UT-DSAEK: has the debate been finally concluded?

In recent years the surgical treatment of corneal endothelial dystrophy has progressed tremendously. Descemet’s membrane endothelial keratoplasty (DMEK) is the newest iteration in the line of rapid surgical advances that has taken place. However, the previously accepted gold standard prior...

Allergic eyelid dermatitis

This is a retrospective 12 year review of 61 patients diagnosed with periocular allergic dermatitis. The average age was 66 years, with 74% being female. The commonest indications for referral were epiphora, ectropion and blepharitis; and the main symptoms were...

Reduced angle after BT for postop diplopia test

The authors undertook a retrospective study to evaluate the extent of reduced deviation after Botulinum toxin (BT) when used as a postoperative diplopia test. They evaluated effect in 39 patients: 32 exotropia and seven esotropia. The same BT dose was...

Myectomy with or without proximal end tucking for inferior oblique overaction

This study aimed to compare the outcomes and impact of inferior oblique muscle myectomy with and without tucking the proximal end of the muscle into Tenons capsule in two surgical groups as a treatment for inferior oblique overaction. Tucking the...

Low cost drainage device use in paediatric glaucoma

This is a prospective study from a tertiary referral centre from India of 34 eyes (31 patients) under 16 years with uncontrolled refractory glaucoma with medical treatment. A low cost glaucoma drainage device (GDD) – Aurolab aqueous drainage implant (ADDI),...

Demystifying external trainee selected components and out of programme experiences

If you don’t know your external TSCs from your OOPC/OOPT/OOPE/OOPR, then this article is for you. Trainee selected components (TSC) are College-approved periods of training, usually ranging from six months to a year (formally ASTO) of intensive subspecialty training in...