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Uveitic glaucoma

The purpose of this retrospective study from two tertiary Institutions in Israel over a period of 13 years, is to present the long-term outcomes of uveitic glaucoma and to identify risk factors for progression. The study included 34 patients (53...

Eye drop prescription and usage in glaucoma patients

The authors describe a study using a questionnaire to determine how patients use their glaucoma medications to investigate the association between patterns of eye drop prescriptions and medication use. They enrolled 67 Japanese patients who had been prescribed topical anti-glaucoma...

Full thickness macular hole after YAG PI

The authors report a case of macular hole post YAG peripheral iridotomy (PI) of a patient with pre-existing vitreomacular adhesion. Although a relatively safe procedure, some anterior segment complications are well documented such as corneal endothelium damage, rise in IOP,...

Adolescent optic disc haemorrhages

The authors conducted this study to describe the clinical characteristics of multi-layered optic disc haemorrhages in adolescents. This was a retrospective review of 16 eyes (11 right and five left) of 16 patients with a mean age of 15 ±2.6...

Long-term open angle glaucoma cohort study

This was a study to estimate the development of open angle glaucoma (OAG) in a screened and re-examined elderly group as compared to an unscreened group during the same time period. The participants comprised of 856 individuals born in 1915...

Reported cases of hemifield slide phenomenon

This article reports three cases of hemifield slide, a phenomenon whereby there is an inability to stabilise and fuse visual hemifields. It occurs with heteronymous visual field loss and is thought to result from the loss of corresponding retinal points....

IOOA and DVD surgery

The authors report the results of bilateral modified inferior oblique (IO) transposition considering the equator in seven patients with infantile strabismus syndrome with inferior oblique overaction (IOOA) and dissociated vertical deviation (DVD). Mean age was 4.5 years (2-7) and mean...

MicroRNA mediate retinoblastoma signal transduction

MicroRNAs (miR) are small non-coding single-stranded RNA molecules, normally 22 nucleotides long. There is a large family of miR that control protein expression by binding to mRNAs, leading to their degradation. One important role of miR is in tumours where...

MicroRNA inhibits corneal neovascularisation

MicroRNAs (miR) are small non-coding RNA that target mRNA for destruction. MiR target about 30% of the protein coding genes and fine tune their expression. MiR have been shown to be involved in several cellular processes including cell cycle, tissue...

Corneal stroma modelling under hypoxic conditions

The cornea is exposed to hypoxia under several conditions including sleep, inflammation and wound healing. Being an avascular tissue to maintain transparency, how the cornea homeostatic controls oxygen tension is important. To address this process two models were utilised; a...

PD-1 and PD-L1 in exenteration specimens

This is an immunohistochemical study looking at variation in the expression of the programmed death-1 receptor (PD-1) and the programmed cell death ligand-1 (PD-L1), comparing cutaneous malignancies which invaded the orbit with uncomplicated nodular basal cell carcinomas. The authors retrospectively...

Correlation between structural and functional status of optic nerve and retina in multiple sclerosis

Multiple sclerosis (MS) involves autoimmune inflammatory demyelination and axonal degeneration in the central nervous system. Investigation of the retina and optic nerve head (ONH) is an ideal way to visualise this demyelination. This study investigates the functional and structural properties...