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Prognostic factors for visual acuity in patients with LHON after gene therapy

This retrospective study investigates prognostic factors affecting the visual acuity after a single intravitreal injection of rAAV2-ND4 gene therapy in 53 patients with Leber’s hereditary optic neuropathy (LHON) with mutation at site 11 778. Patients were reviewed one and three...

Money is a problem, but the problem is bigger than money

The argument surrounding doctors’ pay remains an ongoing battle. At the time of writing, Foundation Year 1 doctors have voted in favour of industrial action due to the lack of substantive employment or regular locum work at the end of...

Bovine pericardium scleral patch graft associated scleritis: Ahmed valve implant for pupillary block glaucoma

Processed bovine pericardium is a lyophilised collagen sheet used as a surgical armamentarium. It renders the material antigenically inert with minimal inflammation [1]. Sclera patch pericardium graft (Tutopatch) is a collagenous membrane derived from solvent preserved, irradiated bovine pericardium [2]...

Handbook of Pediatric Retinal OCT and the Eye-Brain Connection

Paediatric optical coherence tomography (OCT) imaging of the eye remains an evolving technology to date. This handbook delves into this challenging area successfully and gives a comprehensive and detailed input into paediatric OCT pertaining to the retina and the optic...

What's trending Dec/Jan 2023

A round-up of the eye related hot topics that have been trending on social media over the last few weeks. #frightnight #halloween #protectyoureyes The Royal College of Optometrists advised the public against wearing novelty contact lenses this Halloween. In a...

Introduction of the Mydriasert insert at the Manchester Royal Eye Hospital

The authors report on a study to examine the effects of the Mydriasert insert on time, effects, patient comfort and tolerability at Manchester Royal Eye Hospital. Mydriasert is an insoluble ophthalmic insert indicated for mydriasis prior to ophthalmic surgery, which...

A single intravitreal bevacizumab in the treatment of breast carcinoma related choroidal metastasis

Case report Choroidal metastasis represents a common form of intraocular malignancies occurring in up to 10% of patients with systemic metastasis [1]. The most common primary sites of ocular metastasis are breast carcinoma in women and lung carcinoma in men,...

A Nightmare on Doctor Street

“Number one: you can never have sex. Big no no! Big no no! Sex equals death, okay?Number two: you can never drink or do drugs. The sin factor! It’s a sin. It’s an extension of number one.And number three: never,...

Heidelberg Engineering supplies free protective breath shields

Heidelberg Engineering has announced that it is shipping protective breath shields free of charge to SPECTRALIS owners in the UK.

Features of childhood cases of sixth nerve palsy

Based on limited information available for cranial nerve palsies in children, the authors aimed to collect data on new onset paediatric sixth nerve palsies in a UK population. This was a retrospective study over 10 years for children aged <18...

Halloween contact lens trend could put sight at risk, warns ABDO

As Halloween approaches, the Association of British Dispensing Opticians (ABDO) is urging consumers to think carefully before purchasing novelty cosmetic contact lenses online or from non-professional sources. ABDO continues to highlight the widespread lack of awareness regarding the risks associated...

Cavernous sinus thrombosis and orbital cellulitis

This is a report of six cases of combined orbital cellulitis and infective cavernous sinus thrombosis, with a literature review. The average age was 39 years, four were male and two were intravenous drug users. All had sinusitis, usually involving...