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A novel integrated practice unit (IPU) approach to periocular skin cancer management
The COVID-19 pandemic was one of the biggest challenges to face NHS workers. However, history has repeatedly shown that times of difficulty can result in the development of significant social and technological advances. We describe our own experience of this...
Clinical Techniques in Ophthalmology
Ophthalmology is a highly specialised field with complex equipment often unfamiliar to medical students and foundation doctors due to limited exposure during training. Clinical Techniques in Ophthalmology is a 300-page handbook divided into six sections: Basic Clinical Optics, Ophthalmic Equipment,...
Retinoblastoma chemotherapeutic drugs and their toxic effects on RPE cells
There is reported clinical evidence of retinal pigment epithelium (RPE) alterations after intra-arterial (IAC) and intravitreal chemotherapy (IViC) of retinoblastoma. The purpose of this study was to investigate the cellular toxic effects of melphalan, topotecan and carboplatin on the RPE...
Aflibercept, bevacizumab or ranibizumab for diabetic macular oedema
Macular oedema (MO) is a leading cause of visual impairment in patients with diabetic retinopathy. Whilst laser photocoagulation therapy has been the proven treatment for decades, studies over the last five years have also established a role for anti-VEGF agents...
Update: Non-infectious retinal vasculitis
This review article summarises the update on non-infectious retinal vasculitis (RV). It is primarily classified based on the type of retinal vessels involved and further sub-classified as occlusive or nonocclusive. Clinically it can occur as an isolated ocular entity or...Ophthalmology in ancient india, Sushruta’s time and the modern era
While reading an article related to the history of Indian ophthalmology, I came across this description of a surgical procedure: “The doctor warmed the patient’s eye with the breath of his mouth. He rubbed the closed eye of the patient...Optical coherence tomography – reinventing the eye examination
It has been 25 years since Huang et al. presented the first optical coherence tomography (OCT) images in Science [1]. With vast improvements in OCT technology over the years, it is now possible to acquire high-resolution cross-sectional images of the...Has ‘reduce, reuse and recycle’ gone too far?
The past few decades of surgery since the ‘mad cow disease’ have been dominated by a push to switch to disposable instruments. The reason is to prevent cross-contamination and reduce the risk of surgical site infections – especially so with...Evil in the east
I previously related a series of diary entries from an old, unlabelled, leather-bound journal which I discovered last year whilst clearing out the departmental ophthalmic library at my hospital. I had stopped reading it from January 1909 onwards as the...
Vitrectomy after ocriplasmin for VVMT adhesion of MH study
This is a multicentre retrospective study of 51 eyes that received intravitreal ocriplasmin between January 2013 to January 2014 for symptomatic vitreomacular (VMT) +/- macular hole (MH), and then went on to PPV for persistent pathology, comparing a control group...
Support for patients with nystagmus
This is a qualitative study in patients with nystagmus identified through regional clinics, charity events and the Royal National Institute of Blind People (RNIB). Two hundred and fifty-one participants were identified, with 184 respondents included in the study. Fifty-six percent...
