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Brn3b neuroprotective effect in rat glaucoma model

An adeno-associated virus-directed overexpression of the Brn3b protein in hypothesised to confer neuroprotective effects in this paper. This is ultimately tested in a well-accepted rat glaucoma model (Morrison’s model: saline injection into episcleral veins of rat eyes with a force...

Simulation in ophthalmology: a pedagogic viewpoint

The advent of simulation technology has enhanced modern medical training. The first utilisation of simulation was in 1929 where Edward Link used this concept to develop a mechanical flight simulator [1]. Industries such as aviation, nuclear power and the military...

Changes in corneal endothelial layer after strabismus surgery

The purpose of this study was to investigate the changes in the corneal endothelial layer by specular microscopy after surgery in patients with horizontal and oblique strabismus. Eighty-three eyes of 56 patients were evaluated prospectively. There were three subgroups: one...

Contract signed to build Oriel, a state-of-the-art eye health centre

A £300 million contract has been awarded to Bouygues UK to build Oriel, a new eye care, research and education centre in Camden.

Results of STENTube for lacrimal intubation

The STENTube is designed with a varied diameter – a thin central segment with a diameter of 0.86mm and distal tube segments with larger 1.3mm diameter. The thin central segment is exposed at the medial canthus. The distal tubes tamponade...

A possible biomarker for diabetic retinopathy

Diabetic retinopathy (DR) is the most common form of diabetic eye disease, characterised by exudates, microaneurysms and haemorrhage. Early diagnosis is crucial for preventing visual loss. The risk of developing diabetic retinopathy is known to increase with age as well...

Stromal cell alignment in damaged cornea

Stromal keratocytes are responsible for wound healing in the cornea following damage. Keratocytes at the site of injury become activated and differentiate to myofibroblasts which secrete extracellular matrix (ECM) to close the wound, a response mediated by transforming growth factor...

Heidelberg Engineering joins the Collaborative Community on Ophthalmic Innovation (CCOI) through EssilorLuxottica’s Vision Architect membership

Heidelberg Engineering announced that it is joining the Collaborative Community on Ophthalmic Innovation (CCOI) as part of its parent company EssilorLuxottica’s Vision Architect membership – CCOI’s highest level of industry participation. CCOI is a public–private forum that convenes patients, clinicians,...

A new observation point: updating the nomenclature and classification with OCT

The evolution of ophthalmic imaging technologies has been particularly rapid over the last few years. The author provides an update of the current terms for common signs and pathologies observed using optical coherence tomography. My experience as an ophthalmic technician,...

Breakthroughs in the genetics of angle-closure glaucoma

Angle closure glaucoma (ACG) is not widely known to be a familial condition, yet the recent explosion of genetic data and large scale genome wide investigations have confirmed at least 13 genetic loci associated with ACG [1], and provided some...

Features of AMD treatment non-responders

This is a retrospective consecutive case series of 365 eyes with age-related macular degeneration (AMD) who had three monthly intravitreal aflibercept treatments for at least 12 months. Responders were defined as complete resolution of exudation, intraretinal oedema, subretinal fluid, pigment...

What's trending Feb/Mar 2024

A round-up of the eye-related hot topics that have been trending on social media over the last few weeks. #ScleralTattoo #BlackEye Scleral tattoos aren’t necessarily a new phenomenon. A quick google search will identify cases being in the news from...