You searched for "Tumours"
Insights from the ‘Rb-NET Challenges’ Session: Evolving approaches in global retinoblastoma management
The Retinoblastoma Network (Rb-NET) Multidisciplinary Team (MDT) platform, developed by the London School of Hygiene & Tropical Medicine (LSHTM) and Professor Ido Didi Fabian, is a web-based telemedicine initiative that regularly hosts virtual MDT meetings focused on the evaluation and...Pituitary adenoma causing compression of the optic chiasm
A 21-year-old girl presented to her general practitioner (GP) with a three-month history of headaches, becoming more frequent and associated intermittent vomiting that did not improve with simple analgesics. There was a strong family history of migraines. She was initially...
Diagnosis and management of solitary fibrous tumour
This is a retrospective review of 21 patients diagnosed with solitary fibrous tumour of the orbit between 1996 and 2018 at a single centre. The authors reviewed the clinical presentation, management and course of the disease and reanalysed the histopathology...
Developments in Ophthalmology: Ophthalmic Radiation Therapy Techniques and Applications
Radiation was discovered by Wilhelm Roentgen in 1895, and since then has been used to treat a variety of cancers. Its therapeutic properties have been widely used for ocular and periocular tumours and inflammatory disease, but the present era is...
Chronic lymphocytic leukaemia (CLL) of the lacrimal sac
The authors present a case series of three patients with known CLL, two of which presented with mass and epiphora and one case with epiphora alone. All three patients had initially being diagnosed and were treated for chronic dacryocystitis. Histopathological...
Lacrimal gland carcinoma outcomes
This is retrospective review of outcomes of lacrimal gland epithelial tumours treated between 1972 and 2014 at Moorfields Eye Hospital. Seventy-nine patients were reported, comprising 53 adenoid cystic carcinomas, 15 primary adenocarcinomas and 11 carcinomas ex-pleomorphic adenoma. The authors compare...
Quality of life concerns after uveal melanoma diagnosis
The authors sought to investigate factors associated with Quality Of Life (QOL) after initial diagnosis of uveal melanoma (UM) using prospectively collected data between September 2011-May 2016. They included 201 participants referred for radiotherapy after UM diagnosis by an ophthalmic...
Difference in retinoblastoma phenotypes based on maternal or paternal inheritance
The aim of this study was to explore the difference in presentation of retinoblastoma between paternal and maternal inheritance. A retrospective medical records review methodology was employed. Records of individuals diagnosed with a retinoblastoma with at least one symptomatic family...
Therapeutic options for advanced cutaneous basal (BCC) and squamous cell carcinomas (SCC)
This article discusses the use of topical and systemic therapy in the management of advanced periocular tumours. It focuses on those that have gained United States Food and Drug Administration approval; namely imiquimod, vismodegib, sonidegib, pembrolizumab and cemiplimab. Imiquimod is...
Aetiology of painful ophthalmoplegia
Painful ophthalmoplegia is a clinical syndrome presenting with periorbital / hemi-cranial pain and ipsilateral ocular motor nerve palsies and can occur with numerous different diseases. In this study, the authors aimed to determine the final definite aetiology among patients with...
