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Retinal nerve fibre layer thickness in migraine
The aim of this study is to evaluate retinal nerve fibre layer (RNFL) thickness changes in children with migraine compared to healthy controls and analyse RNFL changes dependent on type of migraine. This was an observation case control study of...
A review of neuro and retinal imaging findings in Alzheimer’s disease
The authors present a systematic review with the aim of assessing the relationship between retinal and cerebral changes in Alzheimer’s disease (AD), mild cognitive impairment and pre-clinical AD. A total of 23 articles met the inclusion criteria of the review,...
Changes in C:D ratio of premature infants with enlarged C:D ratios
This retrospective observational study examined the longitudinal alterations in cup to disc ratio (CDR) among premature infants exhibiting enlarged CDR and normal intraocular pressure (IOP) up to two years. Among the 283 infants, 13.4% manifested an enlarged CDR. In this...
Choroid and retinal changes post COVID-19
The authors aimed to evaluate choroid and inner neural layers in people previously recovered from Covid-19 compared to healthy controls using optical coherence tomography (OCT) over a six-month period. They recruited 96 people: 56 with Covid-19 at least three months...
Characteristics of cherry red spot on optical coherence tomography
In this study the authors report optical coherence tomography (OCT) characteristics of cherry red spot from three cases of Tay-Sachs and one case of Niemann Pick diseases to determine associated factors and potential visual implications. This was a retrospective case...
Anti-myelin oligodendrocyte glycoprotein antibody positive optic neuritis: a retrospective medical records review
Optic neuritis causes acute loss of visual function and can result in devastating visual dysfunction. Recently, measurements of anti-aquaporin 4 (AQP4) and anti-myelin oligodendrocyte glycoprotein (MOG) antibodies have become available, making it possible to evaluate the disease pathogenesis. This paper...
Longitudinal findings in children with neurofibromatosis type 1
This retrospective chart review evaluates the ophthalmologic findings of children with neurofibromatosis type 1 (NF1). Optic pathway gliomas (OPGs) are the most common tumours found in children with NF1. Findings are compared between eyes with and without optic pathway gliomas...
A novel parameter for angle closure
This is a population cross-sectional study of 464 eyes that underwent swept-source optical coherence tomography (SSOCT) imaging in the dark. Eight out of 128 cross-sectional images were selected for analysis. Matlab was used to measure the iridolenticular contact area (ILCA),...
Infliximab in treatment of PVR
In this phase 2 randomly controlled trial, 66 patients with primary rhegmatogenous retinal detachment and grade C proliferative vitreoretinopathy (PVR) were randomised in a 1:1 ratio to undergo pars plana vitrectomy (PPV) and silicone oil (SO) injection with or without...
How the thinking machine is transforming the retinal landscape
Regulatory approval of the first two therapeutic substances for the management of geographic atrophy (GA) secondary to age-related macular degeneration has been a major breakthrough. The authors explored the issue surrounding the lack of agreed therapeutic standards and diagnostic tools...
