You searched for "Cataracts"

1233 results found

Autophagy in lens mitochondria loss

The lens consists of a monolayer of epithelial cells that overlies fibre cells that differentiate from epithelial cells at the equator. While developing, fibre cells need mitochondria to provide energy, as they mature they lose these and other organelles to...

Cyclosporine A and pterygium fibroblasts

The matrix metalloproteinases (MMP) are a family of structurally related zinc-dependent extracellular matrix degrading proteinases that have been implicated in facilitating the migration and growth of pterygia. Both MMP- 3 and MMP-13 were found to be overexpressed in the fibroblasts...

Lucentis for pseudophakic CMO

Pseudophakic cystoid macular oedema (CMO) develops angiographically in up to 20-30% after uneventful phacoemulsification. This study aimed to evaluate the potential efficacy and safety of intravitreal ranibizumab in patients with pseudophakic CMO after cataract surgery. Seven eyes were included in...

Ocular characteristics in Marfan syndrome

Marfan syndrome (MFS) is a genetic disorder with clinical manifestations associated with cardiovascular, ocular and skeletal organ systems. Typical signs are descending aortic root aneurysms, ectopia lentis, tall stature and scoliosis. This observational study looked at the ocular characteristics, visual...

Enzymatic clearance of anterior chamber infiltrate in uveitis

Aqueous humour (AH) which fills the anterior chamber (AC) of the eye provides nutrients to the cornea and the lens. Clearance of cellular and particular matter from AH is necessary for good visual acuity. In part this is achieved by...

Risk factors and untreated POAG

The authors examined 50 untreated open angle glaucoma patients to determine if there was an association between the level of glaucomatous damage and documented risk factors. In this study the authors measured the extent of morphologic and functional glaucomatous damage...

Cystoid macular oedema following cataract surgery

This review covers the history, incidence, diagnosis, risk factors, pathophysiology and medical management of postoperative macular oedema (PCMO), with a particular emphasis on key contemporary studies and novel observations. The authors revisit the incidence of well-established risk factors including intraoperative...

The global burden of age-related macular degeneration

Age-related macular degeneration (AMD) is the third leading cause of blindness (behind cataract and refractive error). The authors present the results of the Global Burden of Disease (GBD) 2015 study, which included 195 countries. The disability-adjusted life years (DALY) due...

Viral uveitis

This review covers viral causes of anterior uveitis. A viral aetiology should be suspected when anterior uveitis is accompanied by ocular hypertension, diffuse stellate keratic precipitates or the presence of iris atrophy. Most common viruses associated are herpes simplex, varicella-zoster...

Preoperative anxiety levels and pain during cataract surgery

Increased anxiety has been shown to be associated with greater pain in a number of procedures. In this observational, non-interventional study, the authors sought to evaluate the correlation between pain with phacoemulsification surgery (under topical and intracameral local anaesthesia) and...

Episcleral brachytherapy (EB) for retinoblastoma (RB)

This retrospective study consisted of 11 eyes treated either with Iodine (I) -125 or Ruthenium (R) -106EB with a mean apical dose of 44Gy. There were five in group B (46%), three in group C (27%) and three in group...

Visual outcome and surgical results in children with Marfan Syndrome

Eighty-two eyes of 41 patients with a genetically proven diagnosis of Marfan syndrome were retrospectively analysed. Twenty-seven had bilateral subluxation and 14 received lensectomy. Follow-up was three years. Mean visual acuity (VA) was 0.1 ±0.7 logMAR in patients with normal...