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Inflammatory macular holes
The authors present a case of closure of a full thickness macular hole in a patient with Behçet’s disease, without surgery. The 23-year-old male they describe presented with a history of recurrent oral aphthous ulcers and a genital ulcer. Ocular...
Use of international interocular difference thresholds for optic neuritis diagnosis in clinical practice
Multiple sclerosis (MS) is the most common non-traumatic cause of disability in young people, and visual symptoms can be the initial manifestation in up to 20% of cases. Retinal examination can be helpful in making the correct diagnosis. The latest...
The use of adalimumab for relapse in patients with Vogt-Koyanagi-Harada disease
In this retrospective, multi-centre, cohort study, the efficacy and safety of Adalimumab (ADA) treatment for the exacerbation or recurrence of Vogt-Koyanagi-Harada (VKH) patients was assessed by investigating the medical records of patients who had received ADA treatment for more than...
Impact of initial management on relapse in Vogt–Koyanagi–Harada syndrome
In this retrospective, multi-centre, observational study, the impact of the initial management of Vogt-Koyanagi-Harada syndrome (VKHS) was assessed by reviewing the records of all patients diagnosed with VKHS between January 2001 and December 2020 in two French tertiary centres, with...
Early biomarker for paraneoplastic retinopathy
This informative case series evaluates 4 eyes of 2 patients presenting with rapidly progressive vision loss secondary to cancer-associated retinopathy. The authors identified a distinct spectral-domain optical coherence tomography structural feature termed the angular sign of Henle fibre layer hyperreflectivity...
Risk of non-infectious uveitis associated with medications for substance use disorders
The authors evaluate the risk of non-infectious uveitis (NIU) in patients prescribed medications for medication-assisted treatment (MAT) of substance use disorders compared to a control group prescribed selective serotonin reuptake inhibitors (SSRIs). Utilising aggregated electronic health record data, this retrospective...
Ocular surface and meibomian gland changes in cicatricial conjunctival disease
The authors evaluate long-term structural and functional meibomian gland and lid margin changes in a retrospective study of 64 patients (64 eyes) with chronic cicatricial conjunctival diseases (CCDs), including ocular cicatricial pemphigoid (OCP; n=22), Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS-TEN; n=24),...
