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Study calls for thorough investigation of patients with early signs of retinal vascular disease

Patients with the eye condition Paracentral Acute Middle Maculopathy (PAMM) would benefit from further investigation, as their risk of heart attacks and strokes may be greater than previously shown, suggests a new study led by researchers at Moorfields Eye Hospital NHS Foundation Trust.

AI detects eye changes that lead to sight loss in young people

Use of Artificial Intelligence (AI) can accurately predict when young people with the sight- threatening eye condition kerataconus need treatment to stabilise the cornea and prevent loss of vision. Developed by researchers at Moorfields Eye Hospital and UCL Institute of...

High dose (2.5mg) bevacizumab for postradiation cystoid macular oedema

The authors present a retrospective, interventional case series investigating the efficacy of high dose (2.5mg/0.1ml) intravitreal bevacizumab in the treatment of persistent postradiation (Iodine-125 plaque brachytherapy for uveal melanoma) cystoid macular oedema (CME). Persistent CME was defined as increased or...

Beware the disc in myopic patients

Glaucoma is a chronic and progressive optic neuropathy characterised by damage of retinal ganglion cells. Evaluation of structural damage of the optic nerve is important in glaucoma diagnosis. The ISNT rule states that the neuroretinal rim width is generally widest...

Epiretinal membranes in uveitic macular oedema

Epiretinal membrane (ERM) formation in uveitic macular oedema is a fairly common structural complication of the retina. The authors describe a retrospective case series of 104 eyes of 77 patients with uveitic macular oedema from a tertiary centre. The treatment...

Retinoschisis

In this retrospective study the authors evaluate the effect of pars plana vitrectomy (PPV) and internal limiting membrane (ILM) peeling for lamellar macular hole (LMH) with or without macular retinoschisis in highly myopic eyes. Twenty-one highly myopic patients (22 eyes)...

Intravitreal aflibercept for retinal angiomatous proliferation (RAP)

In this prospective study the authors present the visual and anatomical outcome of patients with RAP lesions who were treated with intravitreal aflibercept. The study cohort of 46 patients reached study completion at week 96. They were all Caucasians, with...

Traumatic macular holes: reconstructive changes in foveal microstructures and visual predictor analysis, following surgical repair

The purpose of this paper was to investigate the reconstructive changes in foveal microstructures postoperatively and analyse the visual predictors in eyes with surgically closed traumatic macular holes (TMHs). This retrospective study analysed the data collected from 71 eyes of...

Verteporfin shortage: treatment options and outcomes in chronic non-resolving central serous chorioretinopathy

Half-dose photodynamic therapy (HD-PDT) with verteporfin has been the therapy of choice in non-resolving central serous chorioretinopathy lasting longer than four months. Since 2021, a worldwide shortage of verteporfin due to manufacturing issues prompted adjustments in treatment practices. This retrospective,...

Primary visual pathway changes in individuals with chronic mild traumatic brain injury

Patients with mild traumatic brain injury (mTBI) often self-report vision disturbance despite showing no reduction of visual acuity or fundus examination abnormality. This prospective, observational, cross-sectional study aimed to determine if using a sweeping array of investigations can help diagnose...

Refined glaucoma referral practice offers prospect of improved capacity and expanded role for primary eye care professionals

Glaucoma is the most frequent cause of irreversible blindness worldwide and the second leading cause of blindness in the UK [1,2]. The global prevalence of glaucoma in 2010 was approximately 3.5% for people aged 40-80 years, according to Jonas et...

What's trending Feb/Mar 2018

A round-up of the eye related hot topics that have been trending on social media over the last few weeks. We are officially in 2018. New year, new you. The clock starts to turn to midnight and suddenly the excess...