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1397 results found

Fungi in chronic anterior blepharitis

In this prospective, non-randomised cross-sectional study the authors demonstrate the presence of fungi in patients with chronic anterior blepharitis of at least two years duration. Eyelash samples were obtained by epilation with sterile forceps and evaluated with PAS staining, fungal...

A case report showing the natural history of papilloedema

The case report describes a 54-year-old woman who developed increased intracranial hypertension due to chronic dural venous sinus thrombosis in the absence of any significant comorbidity. In the years preceding diagnosis, the patient underwent routine diabetic retinopathy screening; however, gradual...

Therapeutic options for advanced cutaneous basal (BCC) and squamous cell carcinomas (SCC)

This article discusses the use of topical and systemic therapy in the management of advanced periocular tumours. It focuses on those that have gained United States Food and Drug Administration approval; namely imiquimod, vismodegib, sonidegib, pembrolizumab and cemiplimab. Imiquimod is...

Myopia in Han Chinese

The authors present a case-control study of 361 patients with high myopia (mean spherical equivalent of -6.0DS or lower, and axial length greater than or equal to 26mm) and 749 healthy controls (mean spherical equivalent -1.0 to +1.0DS). They tested...

Addressing childhood blindness in sub-Saharan Africa

In this article, the authors explore paediatric ophthalmology subspecialist fellowship training in African nations south of the Sahara. Until recently, most African ophthalmologists who wished to pursue a subspecialty ophthalmology training fellowship had to go abroad. There is a huge...

A missed intraocular telescope – an opportunity to re-focus the evidence

Intraocular telescopes allow magnification of the image so that it would be projected into a larger area of the macula, this makes the central defect caused by dry age-related macular degeneration (AMD) smaller. The most common approach is a Galilean...

Acute management of retrobulbar haemorrhage

The authors discuss the importance of rapid diagnosis and correct management of acute RBH presentation to avoid the risk of permanent blindness. Retrobulbar haemorrhage (RBH) is an ocular emergency that occurs due to arterial bleeding in the orbital cavity behind...

Feb/Mar 2015 Quiz 1

A 79-year-old male presented to the ophthalmic emergency department with a three week history of left eye pain. He also reported visual deterioration in the left eye over the same period. He suffered from degenerative myopia, with his spectacle prescription...

Regulatory drug evaluations and expedited review initiatives: EU and US perspectives

The European Medicines Agency (EMA) and United States Food and Drug Administration (FDA) each conduct independent assessments of benefit-risk profile when evaluating applications to market new or modified medicines, and their respective decision-making is guided by distinct legislation, procedures and...

More sensitive visual acuity test for age-related macular degeneration

Age-related macular degeneration (AMD) is the leading cause of blindness in the developed world. Primarily associated with ageing, genetic factors and lifestyle choices such as smoking also play a contributory role. Patients with early AMD, characterised by the development of...

Vitrectomy after ocriplasmin for VVMT adhesion of MH study

This is a multicentre retrospective study of 51 eyes that received intravitreal ocriplasmin between January 2013 to January 2014 for symptomatic vitreomacular (VMT) +/- macular hole (MH), and then went on to PPV for persistent pathology, comparing a control group...

Long-term surgical outcomes after unilateral LR muscle recession

This a retrospective review of medical records from Korea between January 2003 and January 2012 in the Samsung Medical Centre. The long-term outcomes and risk factors for recurrence after unilateral lateral rectus (LR) recession (ULR) in children with small to...