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ICG TTT for retinoblastoma

Transpupillary thermotherapy (TTT) is a specific form of ocular TT using infrared radiation (diode laser). Indocyanine green (ICG) is also used to achieve the optimal phototherapy effect in eyes with minimal pigment. Twenty-one patients with 42 retinoblastomas in 30 eyes...

Effect of topical diclofenac on postoperative PRK pain: RCT

A major disadvantage of excimer laser photorefractive keratectomy (PRK) is pain and discomfort after the surgery, which is thought to be due to damage to corneal sensory nerve fibres or local release of inflammatory substances. Pain only resolves once corneal...

Intravitreal dexamethasone implant for diabetic macular oedema

The authors report on the three-year outcomes of the Ozurdex Dexamethasone (DEX) intravitreal implant multi-centre trial for the treatment of diabetic macular oedema (DME). Patients with DME (best-corrected vision of 20/50 to 20/200 and central retinal thickness of ≥300µm) were...

Swept-source OCT for measuring peripheral anterior synechiae

The authors report on a cross-sectional study looking at swept-source optical coherence tomography (SS-OCT) for measuring the area and degree of peripheral anterior synechiae (PAS) in patients with angle closure glaucoma. The SS-OCT is commercially available, has a laser wavelength...

Injection of methotrexate into silicone oil-filled eyes for grade C PVR

Methotrexate (MTX) is an antineoplastic antimetabolite with immunosuppressant properties. Folate antagonism is known to contribute to the antiproliferative effects of MTX, and release of adenosine from cells and inhibition of polyamines may explain its anti-inflammatory effects. These activities contribute to...

All eyes on Twiggy as she fronts new campaign warning us: don’t lose focus of your eye health

Dame Twiggy Lawson fronts a new public awareness campaign focused on eye health, as cases of macular disease increase with our ageing population.

Long way up

In the first of a series of guest editorials exploring multiple different Learning Curves, Francis Sanders ruminates on motorcycling and environmental guilt. As an avid motorcyclist, I was naturally drawn to the relatively recent sequel series from Ewan McGregor and...

Practice tips: Directions in cataract surgery services and preventing postcataract endophthalmitis

Future directions in the delivery of high quality cataract surgery services and approved intracameral prophylactic approaches to lowering the risk of postcataract infective endophthalmitis were debated by consultant ophthalmic surgeons in a recent London seminar, held at the Royal Society...

Corporate M&A pace gathers momentum

Intensifying franchise competition, maturing product development pipelines and looming loss of exclusivity spur renewed merger and acquisition (M&A) activity in the ophthalmics sector. Rod McNeil reviews recent deals and related strategic developments. AbbVie to acquire Allergan in $63 billion mega-combination,...

Impact of WASH factors on trachoma prevalence

Trachoma is the leading infectious cause of blindness globally. Following a national population-based trachoma survey in Malawi, one round of azithromycin mass drug elimination (MDA) was carried out successfully – that is, the prevalence of trachomatous inflammation, follicular (TF) in...

Dry eye disease treatments come to the fore at 100%

Guidance on setting up, or enhancing, a Dry Eye disease clinic within the practice will be freely available from OSA members exhibiting at 100% Optical: 1–3 March. The ability to diagnose and treat a major irritation for many is winning...

Maximising the ocular surface prior to cataract surgery: The old and the new modalities of treatment

Cataract surgery is among the most commonly performed surgical procedures worldwide. Over time, it has evolved from a lens-extraction procedure into a refractive intervention that demands meticulous perioperative planning and precision to achieve optimal outcomes. Optimisation of the ocular surface...