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Effect of topical diclofenac on postoperative PRK pain: RCT

A major disadvantage of excimer laser photorefractive keratectomy (PRK) is pain and discomfort after the surgery, which is thought to be due to damage to corneal sensory nerve fibres or local release of inflammatory substances. Pain only resolves once corneal...

Intravitreal dexamethasone implant for diabetic macular oedema

The authors report on the three-year outcomes of the Ozurdex Dexamethasone (DEX) intravitreal implant multi-centre trial for the treatment of diabetic macular oedema (DME). Patients with DME (best-corrected vision of 20/50 to 20/200 and central retinal thickness of ≥300µm) were...

Swept-source OCT for measuring peripheral anterior synechiae

The authors report on a cross-sectional study looking at swept-source optical coherence tomography (SS-OCT) for measuring the area and degree of peripheral anterior synechiae (PAS) in patients with angle closure glaucoma. The SS-OCT is commercially available, has a laser wavelength...

Injection of methotrexate into silicone oil-filled eyes for grade C PVR

Methotrexate (MTX) is an antineoplastic antimetabolite with immunosuppressant properties. Folate antagonism is known to contribute to the antiproliferative effects of MTX, and release of adenosine from cells and inhibition of polyamines may explain its anti-inflammatory effects. These activities contribute to...

RNIB puts vital eyecare support in place across Hertfordshire and West Essex

Patients with eye conditions across Hertfordshire and West Essex now have access to vital emotional and practical support as The Royal National Institute of Blind People (RNIB) has employed three specialist officers at hospital eye clinics across the region. The...

A case of ‘60-day glaucoma’

Neovascular glaucoma (NVG) has been called ‘90-’ or ‘100-day glaucoma’ in the past due to its typical development three months after the onset of central retinal vein occlusion (CRVO). In reality, NVG can occur anywhere between two weeks and two...

My Top Five: Innovations in the diagnosis of ocular tumours

Ocular tumours can vary widely in origin, from benign growths to metastases from distant disseminated malignancies. Although rare, ocular tumours pose a significant health and economic burden globally, with ocular cancers accounting for 0.2% of all diagnosed malignancies in the...

Association of subconjunctival haemorrhage with non-accidental injury

This study assessed the frequency and nature of diagnostic work-ups in infants with subconjunctival haemorrhage (SCH), the incidence of occult injuries among these patients and the factors that may have influenced the work-up. This was a retrospective secondary analysis of...

Dry eye disease treatments come to the fore at 100%

Guidance on setting up, or enhancing, a Dry Eye disease clinic within the practice will be freely available from OSA members exhibiting at 100% Optical: 1–3 March. The ability to diagnose and treat a major irritation for many is winning...

Corneal Transplantation

This relatively small book provides a thorough overview of the history of corneal transplantation, an update on the anatomy and physiology of the cornea with particular reference to the components essential to keratoplasty procedures, also graft preparation and storage. There...

Long way up

In the first of a series of guest editorials exploring multiple different Learning Curves, Francis Sanders ruminates on motorcycling and environmental guilt. As an avid motorcyclist, I was naturally drawn to the relatively recent sequel series from Ewan McGregor and...

Corporate M&A pace gathers momentum

Intensifying franchise competition, maturing product development pipelines and looming loss of exclusivity spur renewed merger and acquisition (M&A) activity in the ophthalmics sector. Rod McNeil reviews recent deals and related strategic developments. AbbVie to acquire Allergan in $63 billion mega-combination,...