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My Top Five: Promising gene therapies for ocular conditions

Gene therapy, a pivotal advancement in modern medicine, particularly shines in ophthalmology. By targeting defective genes with engineered vectors, this approach promises significant strides in treating inherited retinal diseases. This article reviews the top five gene therapies in late-stage trials,...

Make eye drops a part of your Ramadan routine

Glaucoma UK, the Muslim Council of Britain (MCB), and the British Islamic Medical Association (BIMA) are encouraging Muslims with glaucoma to continue using their medication as prescribed during the holy month to prevent irreversible sight loss.

Trends in Ophthalmology Meeting 2023

The chill of an early spring day was warmed by the buzz of excitement as nearly 150 attendees arrived in central London for the first face-to-face annual Trends in Ophthalmology meeting since the pandemic. Chaired by Ms Susie Morley, attendees...

SOS (Simplified Ophthalmic Statistics) Part 3: Which statistical test should I use (if any)?

P<0.05 is a statement that brings joy to many researchers. Arguably this is because inclusion of such a statement may increase the chance of acceptance for publication. Whilst statisticians and non-statisticians are united in trying to change this culture, cultural...

The structure function relationship in glaucoma

Chronic open angle glaucoma (COAG) is the second most common cause of blindness worldwide. It is diagnosed on the basis of three clinical signs, raised intraocular pressure (IOP), visual field (VF) defects and structural changes to the optic nerve head...

Warfarin Induced Suprachoroidal Haemorrhage Presenting as Acute Angle Closure Glaucoma

Spontaneous suprachoroidal haemorrhage is a rare but recognised entity. Anticoagulant therapy is a well known risk factor. We describe a case of warfarin induced suprachoroidal haemorrhage presenting as acute angle closure glaucoma in a patient with raised International Normalised Ratio...

What effects do repeated Ozurdex implants have in paediatric uveitis?

The aim of this retrospective study was to assess the anatomical and functional results, as well as complications of repeated Ozurdex intravitreal implants in a paediatric (non-infectious) uveitis cohort. Twenty-two eyes (16 patients) received 35 Ozurdex implants over a six...

Management of giant retinal tears with vitrectomy and perfluorocarbon liquid postoperatively as a short-term tamponade

The authors report an eight year retrospective case series study of 30 eyes of 29 patients with who underwent a giant retinal tear-related retinal detachment repair. M: F ratio was 23:6. Right to left eye ratio was 16:14. The mean...

The results of the last survey Dec20

The responses to the first question in this survey demonstrate the need for it and the significant variation in practice we see in even relatively simple management decisions. Patients are seen regularly with occludable drainage angles and listed for YAG...

Systemic sarcoidosis presenting with acute myopia and angle closure

Case report A 40-year-old Asian man presented to the Emergency Department with a one day history of sudden onset visual disturbance in his right eye. He complained of image distortion and noted that objects now appeared smaller. He also described...

Assessing everyday visual function in dry AMD – what matters to the person?

Age-related macular degeneration (AMD) is the primary cause of blindness in the developed world and is accountable for more than one half of sight impairment registrations within England and Wales [1]. AMD is prevalent in people aged 60 years and...

Dramatic myopic shift due to epithelial basement membrane dystrophy

Epithelial basement membrane dystrophy (EBMD), also known as map-dot-fingerprint dystrophy, is a common anterior corneal disorder affecting approximately 2% of the population [1]. It is characterised by the abnormal maintenance of the basement membrane, resulting in protrusions into the epithelium....