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Herpes zoster ophthalmicus: the essentials

Herpes zoster, also referred to as shingles, is a common infection most typically caused by the reactivation of varicella zoster virus that lies dormant (sometime for decades) in the dorsal root nerve ganglion following primary chickenpox infection [1]. In 10-20%...

What's trending Oct/Nov 2019

#probeyeotic #eyeballbugs #microbiome The human microbiome usually conjures up images of the gastrointestinal tract and yoghurt containing good bacteria. However, research suggests that the ocular mucosa is home to a unique microbe collection, with important immunological functional properties [1]. This...

Artificial intelligence and the 2024 Esme’s Umbrella Medical Student Essay Prize

Esme’s Umbrella is a charity for people with Charles Bonnet syndrome (CBS), helping raise awareness of the condition as well as offering support and advice. All clinical specialties may encounter CBS, so Esme’s Umbrella inaugurated a medical student essay prize...

Age and prevalence of amblyopia in Ghana

The overall aim of this study was to determine the pattern and prevalence of amblyopia and assess the treatment options used in a rural hospital in Ghana. The authors conducted a retrospective study from 2014-2018. Of 12,860 clinical records, 12,602...

Amnion-assisted conjunctival epithelial redirection (ACER): Enhancing stem cell transplantation treatment of total limbal stem cell deficiency

An exploration of Professor Harminder Dua’s recent work using a technique called amnion-assisted conjunctival epithelial redirection (ACER) to aid the success of conjunctival-limbal grafting procedures. ACER provides a refined way to use amniotic membrane (amnion), such as Omnigen® (NuVision® Biotherapies,...

Mast cells in Graves’ ophthalmopathy

Graves’ ophthalmopathy (GO) is a potentially sight-threatening ocular disease, occurring in patients with hyperthyroidism due to Graves’ disease. Also known as thyroid-associated ophthalmopathy, GO is characterised by orbital infiltration by immune cells including macrophages, T cells and plasma cells, which...

How do you solve the problem of trachoma in Ethiopia?

Background Trachoma is one of the oldest diseases known to humankind and the leading infectious cause of blindness worldwide. Spread by the bacterium chlamydia trachomatis, it is transmitted through contact with the eyes, eyelids and nose of those infected. The...

CHEC announces launch of two new treatment centres (1)

New sites in Ilford and Milton Keynes will further extend CHEC’s community-focused endoscopy and ophthalmology services across England.

Protecting retinal ganglion cells

Glaucoma is considered to be a heterogeneous group of conditions giving retinal ganglion cells (RGC) damage. Lowering intraocular pressure (IOP) reduces the risk of progressive RGC loss in glaucoma. Regeneration of the optic nerve has been shown to restore some...

Achieving post-op target range increases success of strabismus surgery in adults

This is a retrospective cohort study of all patients over 12-years old undergoing strabismus surgery under a single surgeon in a tertiary referral centre in Toronto, Canada. The aim of the study is to determine the role of achieving immediate...

Brolucizumab in age-related macular degeneration, HAWK Study

The aim of the study was to collect additional data on efficacy and safety of brolucizumab 6mg intended for commercialization in age-related macular degeneration (AMD) (with an increase in pH and decrease in polysorbate concentration). The HAWK Study was a...

Non-organic visual loss

Patients can present to eye departments with various signs and symptoms (mostly symptoms) with no obvious organic cause. These patients can be labelled with any of a wide range of diagnoses such as functional visual loss, functional overlay, psychosomatic reaction...