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Therapy for limbal stem cell deficiency: cell fate after limbal stem cell transplants

“The beauty of scientific research lies in that the search for answers often yields yet more questions.” A large body of evidence points to the corneoscleral limbal location as the repository of putative epithelial stem cells [1]. Thoft proposed the...

Renewed momentum in ocular gene and cell therapy, broadening application to chronic disease

Gene and cell therapies offer the prospect of ground-breaking new avenues for the treatment of diseases, reflected in a renewed explosion of interest and investment in retinal gene therapy. Rod McNeil reports recent clinical trial readouts across a diverse range...

Use of YouTube videos to show surgical techniques for paediatric cataract surgery

This study aimed to assess the quality of the most highly viewed paediatric cataract surgery videos regarding surgeon proficiency and execution of key techniques. A search for congenital cataract surgery and paediatric cataract surgery was made in YouTube. The top...

The last three patients: general medicine (Patient Two)

For the second reflection in this series (see Patient One here), Professor Jonathan Rees recounts his experiences of the last patient he saw as a medical registrar, telling the tragic story of a young man’s death and the risks that...

Atlas of Glaucoma Third edition

Glaucoma patients constitute a significant proportion of any ophthalmology clinic. Hence, a basic understanding, evaluation and management of the condition form part of the essential clinical skillset of any ophthalmologist. Atlas of Glaucoma is a good read and very useful...

10 daily habits damaging your eyesight and changes you can make to remedy against them

Following World Glaucoma Day on 12 March this year, it is vital that the longevity of our vision is always a priority. However, many of our daily habits contribute to the onset of glaucoma and vision loss.

Strabismus in thyroid eye disease

Pathogenesis Thyroid eye disease (TED) is an auto-immune condition, in the initial phase there is lymphocytic infiltration and oedema of the extraocular muscles with deposition of glycosaminoglycans and hyaluronic acid and adipogenesis, which can lead to an increase in the...

The management of watery eye in an infant with facial dysmorphism

A six-month-old child with facial dysmorphism is brought to the eye clinic with history of watery right eye since birth. How will you manage this child? Causes for watery eye in an infant 1. Overproduction of tears a. Infections b....

Sexually transmitted conjunctivitis – the REALLY sticky eye

Let’s face it, patients with conjunctivitis don’t always produce the most stimulating consultations and most of the time we can manage them in auto-pilot. The prospect of delving into such a patient’s sexual history is not overly appealing, but this...

What's trending Jun/Jul 2018

A round-up of the eye-related hot topics that have been trending on social media over the last few weeks. #BusyPhillips #photokeratitis #sunglasses Last time, we were in the throes of the Beast from the East. Here in the UK, it’s...

Unilateral central scotoma following dengue fever

Case report A 16-year-old Caucasian male was referred to the eye casualty at Nottingham University Hospitals NHS Trust by the infectious diseases unit in September 2013. He gave a history of photophobia, pain on eye movements and central blurred vision...

Intracameral antibiotics in cataract surgery: current evidence base

Following on from our recent online survey*, the authors examine the use of intracameral cefuroxime as the standard of care in cataract surgery. Cataract extraction with intraocular lens implantation is one of the most frequently performed surgical procedures in the...