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Poppers retinopathy: What is it and how do we treat it?

Poppers retinopathy is a relatively unknown phenomenon which afflicts users of poppers but should be considered as a differential in sudden-onset or sub-acute visual acuity loss – particularly in patients with a history of recreational drug use. Raising awareness of...

Non-infectious Uveitis: Well Known, Weird and Wonderful meets You, Me and the Balloons

Installation view from Manchester International Festival 2023 exhibition Yayoi Kusama: You, Me and the Balloons at Aviva Studios. Images © David Levene. On an uncharacteristically salubrious 5 July 2023, the date of the 75th Anniversary of the UK’s NHS, a...

Game show freak

As a child of the 70s and 80s, there were limited television viewing opportunities. For the duration of the 70s there were only three channels, only moving to four with the launch of Channel 4 in 1982. Not only that,...

Congenital cranial dysinnervation disorders (CCDDs)

The term congenital cranial dysinnervation disorder (CCDD) was introduced by Gutowski et al. in 2003 to describe strabismus conditions that result from developmental error in innervation of some of the extraocular muscles. Examples of these conditions include Duane’s syndrome and...

Understanding spaceflight-associated neuro-ocular syndrome (SANS): what do we know?

Introduction Formerly known as visual impairment and intracranial pressure syndrome (VIIP), space-related neuro-ocular syndrome (SANS) is defined by a collection of ophthalmic and neurological findings in astronauts after long-term spaceflight [1]. Changes in the eyeball, such as hyperopic shift, during...

Breakthroughs in the genetics of angle-closure glaucoma

Angle closure glaucoma (ACG) is not widely known to be a familial condition, yet the recent explosion of genetic data and large scale genome wide investigations have confirmed at least 13 genetic loci associated with ACG [1], and provided some...

Biomaterials and Regenerative Medicines in Ophthalmology (Second Edition)

With advancement in science and technology in the last decade, the role of biomaterials and regenerative medicines has become increasingly important in the management of various ocular disorders. This book highlights the role of biomaterials in the restoration of vision...

Retinoblastoma management update (part 1): clinical features, diagnosis and genetics

The first of a two part series, this article will discuss the clinical features, diagnosis and genetic aspects of retinoblastoma. Manoj Parulekar is based at Birmingham Children’s Hospital, one of the two designated national retinoblastoma and paediatric ocular oncology treatment...

What effects do repeated Ozurdex implants have in paediatric uveitis?

The aim of this retrospective study was to assess the anatomical and functional results, as well as complications of repeated Ozurdex intravitreal implants in a paediatric (non-infectious) uveitis cohort. Twenty-two eyes (16 patients) received 35 Ozurdex implants over a six...

Conference Report: UCL Institute of Ophthalmology Summer School 2025

The UCL Institute of Ophthalmology Summer School 2025 was held in collaboration with Moorfields Eye Hospital run by Gordon Hay and Tara Bader. This was a comprehensive five-day course attended by medical students and resident doctors from around the world....

Open globe trauma – visual outcomes after primary vitrectomy

This retrospective study aimed to evaluate the impact of early vitrectomy on visual outcomes in eyes with open globe ocular trauma. One hundred and eighty eyes from a cohort of 166 patients who underwent primary vitrectomy between 2017 and 2023...

The eye surgeon and eye physician together: the joint ophthalmic clinic

Since the early 19th century, physicians and surgeons have been working together in eye clinics and hospitals to bring about the best outcome for the patients. From the early Babylonian age, important advances in ophthalmic knowledge arose in a stuttered...