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Leber’s hereditary optic neuropathy: from lab to clinic
Leber’s hereditary optic neuropathy (LHON) was the first clinically described mitochondrial disorder (1871). This article reviews the pathophysiology and clinical features of LHON with a focus on translational research. G11778A is currently the most common mutation worldwide and is associated...Choroidal folds
Choroidal folds are undulations of the choroid, Bruch’s membrane and pigment epithelium, with wrinkling of the overlying retina. They may be idiopathic but can also be caused by a number of different conditions. Case report A 60-year-old male patient was...Lord Trees and Baroness Sugg call to end Neglected Tropical Diseases with charity coalition at Westminster event
UK Coalition against Neglected Tropical Diseases works alongside co-host parliamentary reception in the House of Lords.Developments in retinal pigmentation measurement and the hopes of an equitable future
Our AI & Oculomics co-editor, Nima Ghadiri, sat down with Abraham Olvera-Barrios from Moorfields and Anand Rajesh from the University of Washington to discuss their recent international study into retinal pigmentation and its wider clinical, technological and academic applications. Can...Optegra launches new fellowship programme
Leading eye health care group, Optegra, is proud to announce the appointment of its first Fellow, Mr Fadi Alfaqawi, as it unveils its Cataract and Refractive Surgery Fellowship Programme.Orbis brings the Flying Eye Hospital to Mongolia to train local eyecare teams
With support from the Alcon Foundation, FedEx, and OMEGA, the Orbis Flying Eye Hospital returns to Mongolia for a three-week training project in Ulaanbaatar.Attending ophthalmology conferences as a foundation trainee: an eye-opener?
The benefits of attending specialty conferences for clinicians are numerous. For example, staying up to date with the latest advancements in the field and integrating these into clinical practice. However, foundation doctors are yet to enter a training pathway and...Urban Changes and Rural Struggles for Ophthalmology in China
China is by far the most populated country in the world, with over 1.3 billion inhabitants. It is also the country with the highest number of blind and visually impaired people. As a developing country, half of China’s population lives...
Trabeculectomy ab interno (trabectome)
This retrospective study examines the outcome of trabectome surgery in nine phakic patients with Posner-Schlossman syndrome with uncontrolled IOP >30mmgHg. Cytomegalovirus (CMV) DNA was verified by polymerase chain reaction (PCR) in aqueous humour samples. Patients were treated with oral valganciclover...Informed consent in ophthalmology care in the UK: A critical component of patient‑centred practice
Informed consent is a cornerstone of ethical and legal practice in healthcare, particularly in fields like ophthalmology where specialised interventions can have significant implications for a patient’s vision and quality of life. In the UK, informed consent is not merely...The David J Apple International Laboratory for Ocular Pathology – a legacy of pioneering IOL research
David Apple and Gerd Auffarth. The Apple Lab at the David J Apple Center for Vision Research in Heidelberg is a thriving international laboratory for research into intraocular devices. The lab continues the work of David J Apple, a world-renowned...
