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Real world data of post-IVT endophthalmitis, from a nurse-delivered intravitreal injection service
Introduction Intravitreal injection of neutralising anti-vascular endothelial growth factor (VEGF) antibody was licenced more than a decade ago, and over the years there has been proportionate increase in the number of intravitreal injections [1]. Injection of a therapeutic agent through...The Worshipful Company of Spectacle Makers awards two Master’s Medals for early career research
The Worshipful Company of Spectacle Makers (WCSM) this week announced the winners of two Master’s Medals for 2025. Fabian Yii from Edinburgh was awarded the Master’s Medal for his paper, 'Fundus Refraction Offset as a Personalized Biomarker for 12-Year Risk...Retinoblastoma management update (part 1): clinical features, diagnosis and genetics
The first of a two part series, this article will discuss the clinical features, diagnosis and genetic aspects of retinoblastoma. Manoj Parulekar is based at Birmingham Children’s Hospital, one of the two designated national retinoblastoma and paediatric ocular oncology treatment...The treachery of images – making sense of OCT imaging
In 1929 Belgian surrealist Rene Magritte produced his painting La Trahison des Images. It depicted an old fashioned pipe for smoking tobacco and underneath were the words “ceci n’est pas une pipe”, this is not a pipe. You may wonder...
Statins inhibit TGFβ2 mediated fibrotic response in astrocytes
Glaucoma is a common condition where increased ocular pressure can lead to death of retinal ganglion cells due to impaired drainage of fluid from the eye. One mechanism involved in glaucoma is remodelling of the extracellular matrix at the lamina...
How common is empty sella in neuro-ophthalmology patients not suspected of raised intracranial pressure
The study aimed to assess how common the presence of empty / partially empty sella is amongst neuro-ophthalmology patients undergoing magnetic resonance imaging (MRI) excluding for papilledema and raised intracranial pressure (ICP). The study retrospectively reviewed case records of consecutive...
Results of bilateral medial rectus recession combined with either BT or bridge Faden when treating large angle strabismus
In a series of 26 patients (11 female, 15 male) with large angle esotropia >35PD, the authors compared results of botulinum toxin A (BTA) and bridge Faden operation combined with bilateral medial rectus (BMR) recession. Overall age of surgery was...
Intraocular pressure reduction after cataract surgery
Several studies have shown the efficacy of cataract surgery in lowering intraocular pressure (IOP), especially in angle closure glaucoma compared to open angle. A total of 156 eyes of 109 patients (without glaucoma or with medically controlled glaucoma) were included....Non-organic visual loss
Patients can present to eye departments with various signs and symptoms (mostly symptoms) with no obvious organic cause. These patients can be labelled with any of a wide range of diagnoses such as functional visual loss, functional overlay, psychosomatic reaction...SOS (Simplified Ophthalmic Statistics) Part 4: How to present your statistical analysis
This is the last in this series of short guides which we hope provide some guidance in relation to statistical issues researchers may encounter when conducting research, audit or indeed quality improvement projects. Here we focus on an issue that...Ultrasound biomicroscopy (part 2): primary angle closure
Patients with primary angle closure or primary angle closure glaucoma [PAC(G)] comprise a significant subgroup affecting around 10% of glaucoma patients amongst Caucasians. Assessment of the patient with angle closure, or narrow angles, requires gonioscopy. However, whilst identifying the presence...
