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Usher syndrome: an overview

Usher syndrome is the most common hereditary condition that affects both vision and hearing. It is an autosomal recessive condition characterised by retinitis pigmentosa (RP) and bilateral sensorineural hearing loss [1,2]. Usher syndrome is the cause of approximately 10% of...

Neonatal hypoxic ischaemic encephalopathy with imaging abnormalities in the occipital lobe – how to counsel the parents

Case A baby boy, with a background of intrauterine growth restriction, was born at 37 weeks and three days gestation via forceps delivery. The baby was born in poor condition, with low heart rate, poor respiratory rate, poor colour and...

The last three patients: general medicine (Patient Two)

For the second reflection in this series (see Patient One here), Professor Jonathan Rees recounts his experiences of the last patient he saw as a medical registrar, telling the tragic story of a young man’s death and the risks that...

Where are they now?

The Eye News and University of Edinburgh teams last met up with Zomba-based Dr Chinsisi Namate Nyirenda, in Glasgow, May 2022, when she was a member of The Ophthalmological Society of Malawi’s delegation to the Royal College of Ophthalmologists Annual...

See sweet to C-suite: Imran Rahman

See also - See sweet to C-suite: Peter Holland In this three-part conversation series, Co-editor David Lockington speaks with highly influential individuals about their journey to the top, with advice for the next generation of leaders. Part Two: David speaks...

The world of the unseen

We are witnessing an incredible era of miraculous and marvellous discoveries. The globe has seen breakthroughs in science, medicine, creative arts, technology, digital media, and much more. In warm, sunny April, Emerald Network celebrated its 20th year of Eid events,...

Pioneering eye device restores reading vision to blind eyes

A pivotal European clinical trial of a new electronic eye implant has seen remarkable results. The study, published in the New England Journal of Medicine, showed 84% of participants were able to read letters, numbers and words using prosthetic vision...

Long-term outcome of ALPI for plateau iris syndrome

The purpose of this study was to evaluate the long-term outcomes of plateau iris syndrome (PIS) patients treated with argon laser peripheral iridoplasty (ALPI) following YAG laser peripheral iridotomy (LPI). Typical ALPI settings were a spot size of 200 to...

Steroid implants in the treatment of post-epiretinal membrane peel macular oedema

This is a retrospective review of 39 eyes of 37 patients treated with Ozurdex® (intravitreal dexamethasone implant) for persistent post-operative cystoid macular oedema (CMO) following vitrectomy and idiopathic epiretinal membrane (ERM) peeling. The 0.7mg implant was injected in each eye...

Multimodal imaging in wet AMD

This novel study set out to determine grader agreement levels of various retinal imaging techniques, commonly used in the diagnosis of wet age-related macular degeneration (AMD). Images from 52 eyes were by examined by two different observers. All images were...

My Top Five: Key insights from recent research into uveitis in adults

Uveitis, characterised by inflammation of the uvea – the eye’s middle layer comprising the iris, ciliary body, and choroid – remains a leading cause of visual impairment worldwide [1]. It primarily affects adults aged 20–50 years. Untreated uveitis may cause...

Differential inhibition of EAU by CTLA4 and IL-6

Cytotoxic T lymphocyte antigen-4 (CTLA4) binds both CD80 and Cd86 and inhibits T lymphocyte activation via CD28. Il-6 is a pleiotropic cytokine that has been associated with many autoimmune conditions including uveitis. Blockade of these molecules by either CTLA4-Ig, a...