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Intravitreal Ziv-Aflibercept: safety analysis
Ziv-Aflibercept (Zaltrap; Sanofi-Aventis U.S LLS, Bridgewater, NJ) was originally introduced as an intravenous formulation for metastatic colorectal cancer. The adoption of Ziv-Aflibercept in ophthalmic practice was similar to bevacizumab, and reports have previously examined one to two year visual outcomes...PACK-crosslinking for infectious keratitis
Corneal cross-linking with riboflavin and UV-A light (CXL) is a technology that has been initially developed to treat corneal ectatic disorders [1]. Its effect in stabilising diseases such as keratoconus was reported in numerous trials with excellent long-term outcomes and...
Infantile exotropia surgical outcomes
This study investigates the success rate and dose response of bilateral lateral rectus muscle recessions (BLL) and bilateral lateral rectus muscle recessions plus unilateral medial rectus resection (LMR) on basic type infantile exotropia of 20–45PD. This was a retrospective review...
Horizontal angles in Brown’s syndrome
The purpose of this study was to determine the incidence of horizontal strabismus needing surgical management in Brown’s syndrome. This was a retrospective review of 19 eyes (eight right and 11 left) of 16 patients (seven male and nine female)....Myasthenia Gravis Masquerading as a Third Cranial Nerve Palsy
A 65-year-old man presented with a week’s history of binocular diplopia (in all directions of gaze) and a right partial ptosis. He was systemically well. His past medical history was unremarkable except for vitiligo. At presentation acuity was 6/6 bilaterally....
The Lacrimal System Diagnosis, Management and Surgery (Second Edition)
The lacrimal drainage apparatus is an intricate conduit, the function of which depends on a complex interplay of its morphology and physiology. This book enhances our understanding of the disorders of the nasolacrimal system, their diagnosis, management and the surgical...High-stakes scenarios in retinal vein occlusion: A survey of medico-legal implications
Central retinal vein occlusion (CRVO) is the second most common retinal vascular disease after diabetic retinopathy, and its clinical complexity often intersects with medico-legal scrutiny [1]. Missteps in timely diagnosis, inadequate follow-up or poor documentation can lead to patient harm...
Using fusion measures to guide strabismus surgery
In this study the authors targeted patients with non-accommodative decompensating distance esotropia with investigation of prior binocular single vision. Choice of target angle was based on the individual’s fusional amplitudes. The target angle aimed to be less than the distance...My Top Five: Emerging technologies revolutionising ophthalmology
Advancements in ophthalmology have significantly transformed eyecare practices. This article explores five emerging technologies that are revolutionising the field, from virtual reality (VR) surgical training to novel therapies for corneal conditions. These innovations are reshaping how eyecare professionals diagnose, treat...
Conjunctivochalasis and aqueous tear deficiency – which one causes symptoms?
This review sought to determine whether conjunctivochalasis (CCh) obliterates the fornix tear reservoir and thus mimics aqueous tear deficiency (ATD). Patients were divided into two groups, with aqueous tear deficiency (CCh +ATD) or without (CCh –ATD), based on results of...An Inconvenient Truth: Pete’s hidden curriculum Part 4
“What gets us into trouble is not what we don’t know. It’s what we know for sure that just ain’t so.” The above is a quote attributed to Mark Twain from the 2006 documentary, An Inconvenient Truth, which follows Al...
