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IAC vs. IVC chemotherapy for RB

This a single centre retrospective review of consecutive patients between 1997 and 2014, of all sporadic unilateral retinoblastoma (RB) group D cases, treated with combined intravenous chemotherapy (IVC) and focal treatments (1997- 2008), or intra-arterial chemotherapy (IAC) treatment (2008 to...

Medial rectus anatomy in exotropia

This study investigates the differences between extraocular muscles in patients with intermittent exotropia and normal controls regarding muscle fibre arrangement and diameter, and distribution and activation of satellite cells. Fifteen patients were recruited having medial rectus resection surgery. Resection sections...

Diplopia after orbital decompression

This is a review of patients undergoing a balanced two-wall and fat orbital decompression to identify risk factors for new onset diplopia. Standard decompression techniques were used, but as the surgery was conducted by ENT surgeons, the medial walls were...

Incomplete teprotumumab treatment for thyroid eye disease

This is a multi-centre retrospective analysis of clinical outcomes in patients who were on teprotumumab for thyroid eye disease but had the usual regime of eight infusions, three weeks apart, interrupted due to COVID-19. Manufacturing was suspended between Dec 2020...

Using modified staging criteria to determine optic nerve invasion in retinoblastoma

This paper reports the use of a modified staging criteria for optic nerve invasion in extraocular retinoblastoma and its correlation with treatment outcomes in 21 patients. The average age at presentation was 41 months (7–120) and there were 14 unilateral...

Features of bacterial orbital cellulitis on MRI imaging

This multi-centre retrospective study from Australia and the UK examined the quantitative and qualitive parameters of magnetic resonance imaging (MRI) imaging in bacterial orbital cellulitis. Twenty MRI scans from 20 patients with pre-septal and orbital fat involvement (mean age: 40.8...

Use of AI apps in providing information about paediatric ophthalmology

The authors evaluated the reliability and accuracy of responses given by 3 AI apps to questions related to paediatric ophthalmology. One-hundred multiple choice questions specific to paediatric ophthalmology were selected from the OphthoQuestions questionnaire bank (4551 questions on this platform)....

Choroidal and retinal vascular changes after horizontal rectus surgery

The authors used wide field swept-source OCT angiography (SSOCTA) to evaluate changes in retinal and choroidal blood flow before and after horizontal rectus muscle surgery. They aimed to characterise the haemodynamic impact of extraocular muscle surgery on the posterior pole...

My Top Five: Emerging robotic and automated innovations in ophthalmological surgery

Robotic technology is redefining the landscape of ophthalmological surgery by enabling micron-level precision and control beyond human capability. Intraocular microsurgery remains challenging to perform, with concerns about accuracy, tremor, precision, depth perception and dexterity. Moreover, conventional surgical tools have only...