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Conventional vs. accelerated cross-linking

The Dresden protocol of 3mW/cm2 irradiance for 30 minutes has been extensively studied and has shown advantageous clinical and topographical results. However, this protocol is time-consuming and therefore accelerated CXL using higher irradiance to shorten treatment duration has emerged. The...

Transferring imaging from primary to secondary care (part 1)

Transferring clinical imaging from high street optometrists to secondary care is an increasingly requested option, especially in the context of the COVID-19 pandemic. A wide variety of solutions exist to allow this, each with their own merits and shortcomings. For...

The assessment of pupils and 
pupillary reactions

Understanding pupillary reactions is vital in understanding basic neuro-opthalmology. It is a skill required in eye casualty, clinics and perhaps most importantly, exams. To start at the beginning, the pupil is the central aperture of the iris, its size controlling...

What about the children? Cornea cross-linking for children with keratoconus

Keratoconus can behave more aggressively in paediatric than in adult patients. Collagen cross-linking has been shown to slow the progression of keratoconus in adults. This systematic review determined the effectiveness of corneal collagen cross-linking (CXL) in children. For this study,...

An update on inherited retinal disorders (part 2): Approaches to therapy for IRDs

Part 1 of this topic can be found here There are currently no proven cures for inherited retinal disease (IRD). However, multiple avenues of research are being investigated to better understand disease mechanisms and trial potential therapies that may slow...

A pulsatile pump in the TM, a new concept in trabecular outflow research

This is a research article where the authors propose a new model in conceptualising the mechanisms involved in the aqueous outflow at the trabecular meshwork (TM). The authors demonstrated evidence of a pump within the Schlemm’s canal. A pulse generated...

See sweet to C-suite: Peter Holland

See also - See sweet to C-suite: Imran Rahman In this three-part conversation series, Co-editor David Lockington speaks with highly influential individuals about their journey to the top, with advice for the next generation of leaders. Part One: David speaks...

How to get the most out of your ophthalmology elective

If you are in your penultimate year (or even earlier) and have already decided that you want to do ophthalmology, good for you! Ophthalmology is one of the most competitive specialties, and one of the easiest ways to demonstrate your...

The tragedy of the commons

I am a big fan of the YouTube channel Extra Credits History, in which interesting historic events are explained in breathtakingly simple detail in 10 animated videos. I have watched every episode, including the ‘Early Christian Schisms’ and ‘The South...

Management of proliferative diabetic retinopathy

Diabetic retinopathy is a major cause of blindness in the working-age population. Due to the worsening global epidemic of diabetes, the incidence of morbidity caused by the disease is set to increase [1]. The prevalence of diabetes in the UK...

Stem cell transplantation and pterygium surgery

Pterygium is a benign, fibrovascular overgrowth of bulbar conjunctiva extending onto the cornea and has been associated with ultraviolet (UV) light exposure. The prevalence of pterygium worldwide varies between geographical zones but has been reported to range between three and...

Congenital and paediatric cataract: Advances in diagnosis and management

Congenital and paediatric cataracts are relatively rare, although prevalence varies significantly between countries, influenced by factors such as nutrition, immunisation policy and population genetics [1]. In the UK, around 3–4 of every 10,000 babies are born with cataracts. It’s a...