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Are single IOP measurements adequate for estimating the effect of IOP lowering interventions?
The World Glaucoma Association recommends that, to assess the effect on intraocular pressure (IOP) of medication or surgery, the mean of multiple measurements of postoperative IOP is a better reflection of IOP than a single measurement of postoperative IOP. The...
An educational intervention to improve adherence to high-dosage patching regimen for amblyopia
This is a randomised trial of patients recruited between the periods of March 2006 and March 2008 from ophthalmology clinics in the Leicestershire area. A total of 62 children with newly diagnosed amblyopia were allocated randomly into two treatment arms...
Comparison of ganglion cell thinning in glaucoma vs. macular hole repair
This prospective study compared the changes in the photopic negative response of the focal macular electroretinogram (fmERG) caused by retinal ganglion cell complex (GCC) thinning at the macula between patients with open angle glaucoma (OAG) and 12 months after successful...
Inhibiting high-risk corneal allografts
The cornea is an immune privileged site and as such corneal transplants are very successful. However, in situations where this privilege is lost the failure rises substantially. To combat rejection inhibition of the immune responses depends on steroids and other...
Adjunctive topical 5-FU vs. MMC for surgically excised, localised OSSN
Ocular surface squamous neoplasia (OSSN) comprises a range of dysplasia including corneal-conjunctival intraepithelial neoplasia and invasive squamous cell carcinoma. The traditional treatment for localised non-invasive OSSN has been surgical excision with or without intraoperative cryotherapy. Postoperative adjunctive topical chemotherapy significantly...
Bleb-related infection after mitomycin C trabeculectomy
The authors report on the results of the Collaborative Bleb-related Incidence and Treatment Study (CBIITS), which was a five year multi-centre prospective study designed to investigate the incidence of bleb-related infection following filtering surgery with mitomycin C. In this study,...
Non-arteritic anterior ischaemic optic neuropathy in the Asian population
This article provides an evaluation of changes in visual function associated with non-arteritic anterior ischaemic optic neuropathy (NAION) among Korean patients. Visual changes were identified as a reduction in visual acuity by three Snellen lines or a deterioration of visual...
Case series of posterior scleritis
This report aimed to facilitate the correct diagnosis of posterior scleritis, a condition which is usually overlooked or misdiagnosed. Electronic health records of 31 patients with posterior scleritis were analysed and compared to a group with isolated anterior scleritis of...
Ranibizumab versus laser in diabetic macular oedema (LUCIDATE study)
The aim of this study was to compare the functional and structural effects of Ranibizumab versus macular laser treatment in patients with diabetic macular oedema. It was a single centre, prospective, randomised, single masked clinical trial spanning a 48 week...
Progression of myopic maculopathy after treatment
The authors report on a retrospective study carried out to evaluate long-term progression of myopic maculopathy and functional outcome in eyes treated for myopic choroidal neovascularisation (CNV) and in eyes without CNV. Fifty-four myopic eyes of 30 patients were included...
Low dose steroids for ocular dry eye disease in graft vs. host disease
This double-masked randomised clinical trial compared the response of dry eye disease (DED) to treatment with topical steroids in patients with and without graft vs. host disease (GVHD). Forty-two patients in a single centre (n=21 with and n=21 without GVHD)...
