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Retinal structural features of CMV retinitis
Confocal adaptive optics (AO) technology has enabled cellular level retinal imaging, including imaging of photoreceptors and blood flow. Adaptive optics scanning laser ophthalmoscopy (AOSLO) is a technology that provides high resolution and high contrast retinal images by correcting ocular aberrations....
The inflammatory side-effect of Brimonidine
Brimonidine is a well established selective alpha-2 adreno-receptor agonist, used to lower intraocular pressure. This case series reports on 19 eyes affected by brimonidine induced uveitis. Mean age of the patients was 74 years and mean duration of brimonidine use...
Risks factors for graft preparation failure in DMEK
Diabetes mellitus (DM) makes it more difficult to prepare descemet membrane epithelial keratoplasty (DMEK) grafts due to the ‘stickiness’ of Descemet’s membrane. This retrospective study examined a classification system, where donors were scored points according to their DM related risk...
Penetrating keratoplasties in infants
This retrospective review looked at endothelial cell counts (ECC) following penetrating keratoplasties (PKP) performed in infants within the first year of their life. One hundred eyes of 71 patients had their first PKP during the study period (1998-2013). In 30%...
Cataract surgery and long-term risk of glaucoma in PEX
The objective of this study was to compare the development of glaucoma and IOP over an extended time period following cataract surgery in eyes with and without pseudoexfoliation syndrome (PEX), and trying to determine the impact of cataract surgery on...
Mast cells in Graves’ ophthalmopathy
Graves’ ophthalmopathy (GO) is a potentially sight-threatening ocular disease, occurring in patients with hyperthyroidism due to Graves’ disease. Also known as thyroid-associated ophthalmopathy, GO is characterised by orbital infiltration by immune cells including macrophages, T cells and plasma cells, which...
ICG TTT for retinoblastoma
Transpupillary thermotherapy (TTT) is a specific form of ocular TT using infrared radiation (diode laser). Indocyanine green (ICG) is also used to achieve the optimal phototherapy effect in eyes with minimal pigment. Twenty-one patients with 42 retinoblastomas in 30 eyes...
Topical cyclosporine A 0.05% for recurrent anterior uveitis
This is a retrospective case-crossover study conducted by reviewing medical charts of patients treated for recurrent anterior uveitis between 2002 and 2011 at the Kellogg Eye Centre by one cornea specialist. The demographics, episodes of anterior uveitis, severity of episodes...
Smartphone ophthalmoscopy vs. slit-lamp biomicroscopy in diabetic retinopathy
In this prospective, comparative, clinical study the authors’ aim was to assess the reliability and accuracy of smartphone ophthalmoscopy as compared with standard slit-lamp biomicroscopy in the grading of diabetic retinopathy. One hundred and twenty consecutive, new, diabetic patients underwent...
Aspheric toric IOL implantation and LRI in eyes with cataracts and astigmatism
This is a prospective study from a single unit to compare the visual outcome of aspheric toric intraocular lens (IOL) implantation and limbal relaxing incisions (LRI) for management of coexisting age-related cataracts and astigmatism. Sixty eyes of 60 patients with...
Froben for anterior scleritis
Flurbiprofen (Froben) is one of the nonselective cyclooxygenase (COX) inhibitors blocking both COX-1 and COX-2 pathways. Agrawal et al. undertook a retrospective cohort study to determine the effectiveness of oral Froben in managing noninfectious, non-necrotising anterior scleritis. One hundred and...
