You searched for "therapeutics"
Real world data of post-IVT endophthalmitis, from a nurse-delivered intravitreal injection service
3 April 2023
| Yasir Khan, Robin Hamilton, Adam Mapani, Catey Bunce, Ranjan Rajendram, Carlos Pavesio
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EYE - General
Introduction Intravitreal injection of neutralising anti-vascular endothelial growth factor (VEGF) antibody was licenced more than a decade ago, and over the years there has been proportionate increase in the number of intravitreal injections [1]. Injection of a therapeutic agent through...
Moorfields: Ocular emergencies level 1
1 February 2025
Designed for optometrists, orthoptists, nurses and other allied ophthalmic health professionals, this module will deliver the knowledge and skills required for the examination, investigation, diagnosis, treatment, and management of patients who present in an ophthalmic emergency setting. Entry requirementsBSc (Hons)...
Effect of the COVID-19 Urgent Eyecare Service on patient referrals to general practitioners and Hospital Eye Service
28 April 2023
| Hafsa Amjad, Nicholas Rumney
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EYE - General
The COVID-19 Urgent Eyecare Services (CUES) was developed to relieve the demands of hospital ophthalmology, aiming to allow patients to have remote consultations and be managed by community optometric practice. This was because access to Hospital Eye Service (HES) Ophthalmic...
Platelet rich fibrin membrane for descemetocele
This case series described the use of a novel technique in the treatment of descemetocele. Three patients developed descemetoceles following infective keratitis with impending risk of corneal perforation. Platelet rich fibrin (PRF) membrane was prepared using 8ml of fresh venous...DALK as an early therapeutic option for Acanthamoeba keratitis
Eleven patients with Acanthamoeba keratitis (AK) were treated by early therapeutic deep anterior lamellar keratoplasty (DALK). All surgeries were performed in patients who had no response to standard medical therapy of chlorhexidine gluconate, propamidine isethionate and neomycin sulphate, within 10-15...Ranibizumab for the treatment of age-related macular degeneration
1 April 2015
| Nana Theodorou
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EYE - Vitreo-Retinal
This multicentre randomised prospective open label study compared 0.5 versus 2mg of ranibizumab in patients with submacular retinal pigment epithelial (RPE) detachment due to age-related macular degeneration. Four treatment regimens were used for the two strengths either monthly for 12...
Pilot trial of virtual reality to treat amblyopia beyond the age of seven years
A pilot double-blind randomised controlled trial is presented. Patients were required to be between seven and 38 years of age, have a diagnosis of anisometropic and / or strabismus unilateral amblyopia, visual acuity in the amblyopic eye between 0.3-1.0 LogMAR...My Top Five: Promising gene therapies for ocular conditions
4 December 2024
| Ameer Khamise
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EYE - Vitreo-Retinal
Gene therapy, a pivotal advancement in modern medicine, particularly shines in ophthalmology. By targeting defective genes with engineered vectors, this approach promises significant strides in treating inherited retinal diseases. This article reviews the top five gene therapies in late-stage trials,...
My Top Five: Promising gene therapies for ocular conditions
4 December 2024
| Ameer Khamise
|
EYE - Vitreo-Retinal
Gene therapy, a pivotal advancement in modern medicine, particularly shines in ophthalmology. By targeting defective genes with engineered vectors, this approach promises significant strides in treating inherited retinal diseases. This article reviews the top five gene therapies in late-stage trials,...
Insights in resistant diabetic macular oedema
5 August 2022
| Sofia Rokerya
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EYE - Vitreo-Retinal
This article gives a bird’s eye review of the different modalities for the treatment of diabetic macular oedema (DME). The debut of anti-VEGFs has brought a paradigm shift in DME management. This treatment has now become a major breakthrough in...
In conversation with Robert MacLaren
2 December 2019
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EYE - Vitreo-Retinal, EYE - General
Professor Robert MacLaren gave the Keeler Lecture at the Royal College of Ophthalmologists Annual Meeting in May 2019 on gene therapy for retinitis pigmentosa. We caught up with him afterwards to find out more. What are the key messages of...
Detecting apoptosis in retinal cells
1 February 2022
| Sofia Rokerya
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EYE - Vitreo-Retinal
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Apoptosis, Glaucoma, Imaging, Neurodegeneration, Retina
This is a review paper in which the authors summarise the transitioning of techniques detecting apoptosis from bench to bedside, along with the future possibilities they encase. Detection of Apoptosis in Retinal Cells (DARC) technology can be used as a...