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Congenital cataract

Congenital cataract is the clouding or opacification of the lens that occurs at birth or weeks after (infantile cataract). They can be unilateral or bilateral and vary in form, size and location, and consequently the visual impact, management course and...

Insights on medical AI for ophthalmology: an update on current perspectives

Artificial intelligence (AI) has immense promise for revolutionising medical practice. Generative AI is a form of AI in which algorithms are trained on datasets that can be used to generate new content, such as text, images or video based on...

My experience of the transition into a specialist orthoptist role

Michelle Dent discusses the process of transitioning into a new role and the pros and cons along the way. An opportunity arose for a permanent, full time, band 7 specialist role in the medical retina (MR) team in the Newcastle...

Differential inhibition of EAU by CTLA4 and IL-6

Cytotoxic T lymphocyte antigen-4 (CTLA4) binds both CD80 and Cd86 and inhibits T lymphocyte activation via CD28. Il-6 is a pleiotropic cytokine that has been associated with many autoimmune conditions including uveitis. Blockade of these molecules by either CTLA4-Ig, a...

γδ T cell depletion does not affect fungal keratitis

Fungal keratitis (FK) is a blinding condition prevalent in agricultural areas of countries such as India and China. The fungus enters the cornea and induces an inflammatory response which leads to tissue damage. Neutrophils are the earliest infiltrating immune cells...

Case reports of neuro-visual consequences of mild COVID-19 in children

Neuro-visual involvement has been reported in numerous patients with severe SARS-CoV-2 disease, mainly among adult patients. In children, such involvement has been reported in rare cases, often in those presenting with severe forms of COVID-19. The aim of this work...

Inaugural IP education session hailed a hit

A pioneering session has brought together a group of independent prescribers to create content ‘for practitioners by practitioners’ for use in real world scenarios.

Broadening horizons in ophthalmology: crafting a varied elective experience

The elective period for medical students is a unique opportunity to immerse oneself in a field of interest. For students interested in ophthalmology, this can offer a dedicated experience for what can otherwise be quite limited through undergraduate rotations. Alongside...

Posner-Schlossman Syndrome (PSS) European Study Group: study protocol and baseline patient characteristics of a multicentre study

This is a retrospective, multicentre (11 centres) study of European patients (total 107; Caucasians in 93.4%). Age ranged between 11 and 76 years with mean age 42 ±15 years. Best corrected vision was >0.5logMAR in 80.3% of the eyes, and...

Deliberate darkness: The systematic weaponisation of blinding in global protests

As eyecare professionals, we spend our entire professional lives fighting to preserve light. We train to master the delicate microscopic topography of the cornea, the retina and the optic nerve, all with the objective of saving our patients from the...

Typical or surprisingly uncharacteristic presentations of neuro-ophthalmic emergencies

Irrespective of geographical location or patient cohort, emergency departments are high risk locations capable of inspiring extreme anxiety and dread in patients and doctors alike. The stress multiplies when a walk-in or referred case is suspected of underlying neurological pathology....

Uveitis in HIV infected persons

Before the advent of highly active antiretroviral therapy (HAART), uveitis, in particular cytomegalovirus (CMV) retinitis, was the most common cause of visual loss in patients with AIDS. HAART has altered the cause of ocular disease in HIV infected individuals by...