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Clinical & Experimental Ophthalmology journal cover image.

Spectral domain OCT vs. confocal scanning laser ophthalmoscope in measuring RNFL thickness

1 June 2014 | | EYE - General
The aim of this prospective study was to compare the retinal nerve fibre layer thickness (RNFL) measurements obtained from the Cirrus optical coherence tomography (spectral domain OCT) with the Heidelberg Retinal Tomograph 3 (HRT3, confocal scanning laser ophthalmoscope). Eighty-eight normal...
Ophthalmic Research journal cover image

Retinal changes prior to hydroxychloroquine toxicity

1 October 2021 | | EYE - Vitreo-Retinal | Ganglion cell layer, Hydroxychloroquine, Optical coherence tomography, Retina, Retinal thickness
In this retrospective longitudinal study, the authors examined changes in retinal layer thickness in patients taking hydroxychloroquine without evidence of retinopathy. Patients were drawn from a hydroxychloroquine screening clinic and required at least two OCT scans, at least one year...

Genetic therapy gives infants life-changing improvements in sight

24 February 2025 | genetics, gene therapy, Moorfields, paediatrics, research, new, AIPL1, Leber Congenital Amaurosis
Four young children have gained life-changing improvements in sight following treatment with a pioneering new genetic medicine through Moorfields Eye Hospital and UCL Institute of Ophthalmology, with the support of MeiraGTx. The children were born with a severe impairment to...

Doctor at large

1 October 2021 | | EYE - Vitreo-Retinal, EYE - General
“In 1930, the Republican-controlled House of Representatives, in an effort to alleviate the effects of the… Anyone? Anyone?... the Great Depression, passed the… Anyone? Anyone? The tariff bill? The Hawley-Smoot Tariff Act? Which, anyone…?” In this memorable scene, the monotonous...

Belfast Eye Conference 2024

22 June 2024 -23 June 2024
by Zina Mobarak, FY1 Doctor, Manchester University Foundation Trust, UK. The Belfast Eye conference was held online over two days, aimed at anyone interested in ophthalmology and focused on delivering informative talks from specialists in various ophthalmic specialties and presenting...

The Lily Foundation celebrates approval of first ever mitochondrial disease treatment by NICE

14 August 2025 | Leber’s hereditary optic neuropathy, idebenone, Pharmacology, new therapies, research
The Lily Foundation, the UK’s leading mitochondrial disease charity, is today celebrating a landmark achievement in the fight against the disease – the first ever treatment for a mitochondrial condition has been approved for use on the NHS in England....

Transforming eyecare with AI at 100% Optical

4 March 2024 | Pearse Keane, AI, Moorfields, UCL, technology, advancement, artificial intelligence, development
“We are drowning in people we need to see in hospital eye services, and some people are going blind as a result. We are looking at nearly 10m hospital appointments for ophthalmology a year, with an approximately 33% increase over...

Haag-Streit launches Eyesi Indirect Ophthalmoscope ROP simulator for retinal examinations on preterm infants

5 April 2024 | Research & Development
The Eyesi Indirect ROP is a mixed-reality simulator that offers a highly immersive training environment for proper device handling, with an embedded, didactically structured simulator curriculum to teach the diagnostic skills required for correct ROP classification.

Redefining healthcare through the eyes

4 February 2025 | | EYE - Cornea, EYE - Imaging, EYE - Neuro-ophthalmology, EYE - General
The future of healthcare is being shaped by innovation in eyecare and in particular a field known as oculomics. This discipline leverages ocular biomarkers to provide insights into various health conditions, including cardiovascular diseases and psychological or neurological disorders [1]....

A tale of two membranes

1 February 2016 | | EYE - Vitreo-Retinal
It was the best of times, it was the worst of times... It was the season of Light, it was the season of Darkness... I am fortunate to work on a vitreoretinal firm at the moment and only a few...

The Leicester Grading System for Foveal Hypoplasia

1 April 2020 | | EYE - Paediatrics, EYE - Neuro-ophthalmology, EYE - Orbit, EYE - General
The University of Leicester Ulverscroft Eye Unit have published the first medical grading system named after the city of Leicester. Infantile nystagmus is characterised by constant and involuntary eye movements and affects 24 per 10,000 people [1]. Onset is usually...

Management of diabetic macular oedema in vitrectomised eyes

1 August 2016 | | EYE - Vitreo-Retinal
Diabetic macular oedema (DMO) is one of the leading causes of blindness; its prevalence is on the rise with progressive increase in numbers of people suffering from diabetes. The management of DMO has evolved significantly over the past few years....