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2165 results found

Long-term outcomes of intravitreal ranibizumab for neovascular AMD

This is a single centre prospective study for the long-term, whole population ‘real-world’ clinical outcomes of ranibizumab therapy in treatment-naïve patients for neovascular age-related macular degeneration (AMD). This study recorded: demographics, Early Treatment Diabetic Retinopathy Study visual acuity (ETDRS VA)...

Epiretinal membranes in uveitic macular oedema

Epiretinal membrane (ERM) formation in uveitic macular oedema is a fairly common structural complication of the retina. The authors describe a retrospective case series of 104 eyes of 77 patients with uveitic macular oedema from a tertiary centre. The treatment...

Rebound phenomenon after IVT triamcinolone acetonide for macular oedema

In this retrospective study, the authors report the rebound phenomenon after intravitreal triamcinolone acetonide (IVTA) injection for macular oedema secondary to diabetic retinopathy (DR) and central (CRVO) or branch retinal vein occlusion (BRVO). The incidence of a rebound phenomenon was...

World Diabetes Day workshop highlights the importance of education to protect the sight of people living with diabetes

Health professionals from all over the world came together to mark World Diabetes Day on 14 November 2022 through an online workshop celebrating progress in development of diabetic retinopathy (DR) services in low-and middle-income countries (LMICs).

Lived experience with vernal keratoconjunctivitis (VKC)

This study was undertaken to explore the experience of living with VKC. Nine families were interviewed – paired interviews with patients and parents using semi-structured approaches (May-October 2018). Interviews continued until data saturation was reached with no new information. The...

Ocular lubrication versus bandage contact lens in recurrent erosion syndrome (RES)

Twenty-nine patients (eight traumatic, five epithelial basement membrane dystrophy, two idiopathic) were randomised using SPSS to either ocular lubricants or bandage contact lenses (BCLs). Only patients previously treated with ocular lubricants were included. Patients with previous surgery, laser treatment, dry...

The results of the last survey Apr23

*Please be aware that this data does not form part of a peer reviewed research study. The information therein should not be relied upon for clinical purposes but instead used as a guide for clinical practice and reflection. My thanks...

Make eye drops part of your Ramadan routine: wake, drops, eat, pray, done!

During the holy month of Ramadan, Muslims fast during daylight hours, abstaining from food and drink between dawn and sunset each day. Ramadan 2020 starts on 23 April and ends around 23 May, depending on the first appearance of the...

Bilateral LR recession for DRS

This study reports the use of bilateral lateral rectus (LR) recessions instead of unilateral LR recession for unilateral exotropic Duane’s retraction syndrome (DRS) with abnormal head posture. This was a retrospective study of seven patients; five female and two male....

Resveratrol protects against steroid induced intraocular pressure

Topical and systemic steroid delivery is a very effective treatment for many ocular conditions but is compromised by raised intraocular pressure which in turn leads to death of retinal ganglion cells and irreversible blindness. This is an important consideration with...

Differential inhibition of EAU by CTLA4 and IL-6

Cytotoxic T lymphocyte antigen-4 (CTLA4) binds both CD80 and Cd86 and inhibits T lymphocyte activation via CD28. Il-6 is a pleiotropic cytokine that has been associated with many autoimmune conditions including uveitis. Blockade of these molecules by either CTLA4-Ig, a...

Statins inhibit TGFβ2 mediated fibrotic response in astrocytes

Glaucoma is a common condition where increased ocular pressure can lead to death of retinal ganglion cells due to impaired drainage of fluid from the eye. One mechanism involved in glaucoma is remodelling of the extracellular matrix at the lamina...