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IVT Aflibercept 2mg in nAMD: XTEND at 3 years

This study investigated the long-term, effectiveness and safety of IVT-AFL 2mg for neovascular age-related macular degeneration (nAMD). XTEND was a multicentre, observational, prospective study, which was conducted across 127 centres across 17 countries with a follow-up period of 36 months....

A standardised strategy for uveitis etiological diagnosis

This was a prospective, non-inferiority, multicentre randomised control trial, which aimed to assess the effectiveness of a standardised approach in the etiological diagnosis of uveitis versus an open strategy, where clinicians could perform any test. The authors developed their standardised...

DALK as an early therapeutic option for Acanthamoeba keratitis

Eleven patients with Acanthamoeba keratitis (AK) were treated by early therapeutic deep anterior lamellar keratoplasty (DALK). All surgeries were performed in patients who had no response to standard medical therapy of chlorhexidine gluconate, propamidine isethionate and neomycin sulphate, within 10-15...

Technique of deep corneal foreign body removal

This article has been verified for CPD. Click the button below to answer a few short questions and download a form to be included in your CPD folder. The objective is to demonstrate a method for the safe and successful...

Moorfields Education: Dry eye course

This is targeted at clinicians working in primary or secondary care who are interested in learning more about diagnosis and treatment of conditions related to the ocular dryness and lacrimal dysregulation. This course will include tutorials for lacrimal syringing and...

Advances and developments in medical retina

The author provides an update on late breaking clinical trial results in neovascular age-related macular degeneration (nAMD) and presentations on diabetes management from the American Academy of Ophthalmology Retina Subspecialty Day, held during the Academy’s annual meeting in Chicago, October...

Ranibizumab safety in pregnancy

Vascular endothelial growth factor (VEGF) plays a pivotal role during pregnancy, and systemic anti-VEGF administration during this period should thus be avoided. VEGF is expressed in multiple embryonic and foetal tissues during development, with the highest levels found in the...

Ocular manifestations of multiple sclerosis: an overview

Multiple sclerosis (MS) is an autoimmune demyelinating disease of the central nervous system (CNS), in which there is dissemination of lesions in time (two or more clinical events) and space (multiple lesions seen on brain and spinal imaging). The pathophysiology...

Descemet stripping endothelial keratoplasty: surgical management of congenital hereditary endothelial dystrophy

This retrospective case series reports the long-term outcomes of Descemet stripping endothelial keratoplasty (DSEK) with suture assisted donor lenticular assisted donor lenticule insertion in paediatric patients with congenital hereditary endothelial dystrophy (CHED). Thirty eyes of 16 patients were reviewed and...

Using video-oculography to record monocular eye movements

The aim of this study was to examine the characteristics of monocular eye movements recorded using video-oculography (VOG). VOG monocular recording has become increasingly popular in comparison to electro-oculographic binocular recording, due to its simple technique. The authors evaluated the...

Outcomes and complications of supramaximal levator resection

This is a report of 35 children with unilateral congenital ptosis who underwent a supramaximal levator resection, involving extensive dissection of levator including cutting Whitnall’s ligament. The average preoperative margin reflex distance to the upper lid (MRD1) was 0.5mm, and...

Evidence shows hand-holding volunteers help significantly reduce anxiety for patients undergoing eye procedure

New evidence from an evaluation carried out by Helpforce for Friends of Moorfields shows that a volunteer’s support can help patients while they have eye surgery under local anaesthetic. 94% say the support helped them feel less anxious.