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Broadening of treatment options for potentially blinding retinal conditions

2 August 2022 | | EYE - General
Rod McNeil provides an update on a promising bispecific antibody recently approved for treatment of neovascular age-related macular degeneration (nAMD) and diabetic macular oedema (DMO) and considers emerging developments in biosimilars to established anti-vascular endothelial growth factor (anti-VEGF) therapies, including...

Emerging therapies for geographic atrophy: complement inhibitors show potential to slow progression and preserve RPE and photoreceptor integrity

5 June 2023 |
Geographic atrophy (GA) is an advanced form of age-related macular degeneration (AMD) characterised by progressive, irreversible loss of the retinal pigment epithelium (RPE) and photoreceptors and is estimated to account for approximately 10% of AMD-related blindness [1-4]. The Age-Related Eye...

Insights on medical AI for ophthalmology: an update on current perspectives

3 June 2024 | | EYE - General
Artificial intelligence (AI) has immense promise for revolutionising medical practice. Generative AI is a form of AI in which algorithms are trained on datasets that can be used to generate new content, such as text, images or video based on...

Optimising the ocular surface by managing meibomian gland dysfunction

1 February 2016 | | EYE - Cornea
Meibomian gland dysfunction (MGD) is ubiquitous. Ocular surface inflammation and irritation are prevalent in most ophthalmology clinics: corneal, cataract, glaucoma, oculoplastic, paediatric, vitreo-retinal, medical retina and refractive surgery. These patients also represent roughly one third of those attending for emergency...

A pituitary tumour from 1927

1 April 2019 | | EYE - Neuro-ophthalmology, EYE - General
The author shares a clinical case from Edinburgh Royal Infirmary’s archives. It is not often in the course of a clinical career that one gets the opportunity to review a patient who had been treated by a pioneer neurosurgeon some...

Patient changes eye colour permanently and has brighter and whiter looking eyes

1 December 2017 | EYE - Cornea, EYE - General
In this new series, Simerdip Kaur takes a look at the latest ophthalmology-related news stories and asks which are scientific reality and which are ‘fake news’. Headline: Patient changes eye colour permanently and has brighter and whiter looking eyes If...

Another plant-based remedy for the eye?

5 June 2020 | | EYE - Cornea, EYE - Glaucoma, EYE - General
Simerdip Kaur takes a look at the latest ophthalmology-related news stories and asks which are based on facts and which are ‘fake news’. Headline: Another plant-based remedy for the eye? What do the nicknames Mary Jane, tea, and 420 all...

Immunoglobulin G4-related ophthalmic disease – what is it? (Part 2)

3 April 2023 |
Part 2: Clinical presentation and treatment (see part 1 here) Introduction IgG4-related disease (IgG4-RD) is understood to have a vast clinicopathological spectrum; nearly every organ has had reported involvement. Similarly, IgG4-related ophthalmic disease (IgG4-ROD) is known to affect nearly every...

Ultrasound biomicroscopy (part 2): primary angle closure

1 December 2016 | | EYE - Glaucoma, EYE - Imaging
Patients with primary angle closure or primary angle closure glaucoma [PAC(G)] comprise a significant subgroup affecting around 10% of glaucoma patients amongst Caucasians. Assessment of the patient with angle closure, or narrow angles, requires gonioscopy. However, whilst identifying the presence...

Idiopathic intracranial hypertension (IIH)

3 June 2021 | | EYE - Neuro-ophthalmology, EYE - General
IIH is a medical condition where the intracranial pressure (ICP) is raised without an obvious cause. The cerebrospinal fluid (CSF) is produced in by the choroid plexus in the lateral ventricles and the roof of the third and fourth ventricles,...

My message to future ophthalmology teaching fellows: Organising an effective ophthalmology placement

2 October 2025 | | EYE - General
Globally, teaching ophthalmology during the undergraduate period presents challenges. The time allocated for it is minimal with substandard exposure [1,2]. Additionally, the number of universities mandating formal ophthalmology education has significantly declined [3]. Research supports the observation that doctors in...

Imaging papilloedema vs. pseudo-papilloedema

4 August 2021 | | EYE - Imaging, EYE - General
Quite often, in the working week as an ophthalmic photographer, you will be given that patient with ‘swollen discs’ to image. These swollen discs could be a number of things, but mainly fall into one of two categories: papilloedema or...