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Correlation between anti-retinal antibodies and proliferative vitreoretinopathy (PVR)
The pathological basis of PVR is not clearly understood and there are no effective medications targeting this condition. This cross-sectional study looked at the possible association of anti-retinal antibodies with patients with PVR and retinal detachment (RD). Aqueous and vitreous...
HtrA1 enhances cell senescence
A genetic basis for age-related macular degeneration (AMD) has been greatly advanced in recent years. The role of identified pathways such as complement factor H in AMD has been widely investigated. However, the effect of other gene variants identified by...
Long-term treatment of blepharospasm using Botulinum Toxin A
The authors report findings from a retrospective single-centre study which aimed to evaluate the efficacy and safety of long-term botulinum A toxin (BAT) treatment in patients with blepharospasm (BPS). Blepharospasm is described as one of the most frequent types of...
Effect of trabeculectomy on corneal endothelial cell loss
This is a prospective study of 117 eyes for two years after trabeculectomy, to investigate the corneal endothelial cell density (CECD) by specular microscopy prior to and after surgery on a six monthly basis. At six, 12, 18 and 24...
Information booklet for eye drop use
On the basis that children may be more at ease and experience less discomfort and anxiety if provided with some control and choices, the authors developed an eye drop booklet in collaboration with children. This study describes the amount of...
Comprehensive review of inherited retinal diseases
The authors offer an up-to-date review of inherited retinal diseases (IRDs). In each section the authors discuss the molecular basis of disease, genotype and clinical manifestation. They also discuss the investigation findings and current evidence in the treatment of the...
Oxymetazoline hydrochloride for improved symmetry in Graves’ disease
Oxymetazoline hydrochloride 0.1% ophthalmic solution has Food & Drug Administration (FDA) approval for use in involution ptosis. It is an alpha 1 agonist and partial alpha 2 agonist that stimulates Muller’s muscle to lift the lid. The authors of this...
