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Diabetes and diabetic retinopathy: Changes in understanding of the disease over the last 25 years and how the UK is helping low-income countries tackle the challenges

Diabetes – a historical perspective Diabetes mellitus (DM) is a chronic disease caused by inherited and / or acquired deficiency in production of insulin by the pancreas, or by the ineffectiveness of the insulin produced. Such a deficiency results in...

Do steroids prevent progression to proliferative diabetic retinopathy (PDR)?

There is continuing debate on the merits of pan-retinal photocoagulation (PRP) for severe pre-proliferative and proliferative DR versus the newer therapies that inhibit vascular endothelial growth factor (VEGF). This has been hotly debated [1] following the publication of findings from...

A guide to utilising your time efficiently to develop clinical and procedural skills as an aspiring ophthalmologist

Ophthalmology often receives limited coverage in the undergraduate medical curriculum, and the availability of foundation programme jobs in this field is also restricted, reducing exposure to this field for aspiring ophthalmologists. Even if you’re not planning to specialise in ophthalmology,...

Investigating the effect of signal strength on mean retinal nerve fibre layer

The aim of this study was to determine the effect of signal strength on mean retinal nerve fibre layer (RNFL) using spectralis optical coherence tomography (S-OCT). Thirty normal subjects were imaged with S-OCT using variably dense Bangerter foils to alter...

Impact of solar eclipses on vision

Solar retinopathy occurs as a result of mechanical and photochemical damage to the retina caused by exposure to excessive light. The authors presented the optical coherence tomography (OCT) and OCT-angiography findings of five patients who looked at the solar eclipse...

The Real Top Gun: Professor Steve Schallhorn

Steve Schallhorn: Fighter Pilot. In the spring of 1987, I travelled to the cinema at Hendon Central in London with some school friends to watch the newly released movie The Witches of Eastwick starring Jack Nicholson and Michelle Pfeiffer. Unfortunately...

The structure function relationship in glaucoma

Chronic open angle glaucoma (COAG) is the second most common cause of blindness worldwide. It is diagnosed on the basis of three clinical signs, raised intraocular pressure (IOP), visual field (VF) defects and structural changes to the optic nerve head...

Ultra-widefield imaging in glaucoma: Documenting hypotony-related choroidal effusions after microshunt surgery

Ultra-widefield (UWF) imaging provides extended visualisation of the posterior segment beyond the traditional 30–50° field of view. It captures a broad view of the posterior pole and periphery in a single, quick, non-mydriatic acquisition. While its role in diabetic retinopathy...

Diclofenac versus Bromfenac after cataract surgery

Non-steroidal anti-inflammatory drugs (NSAIDs) are commonly used after cataract surgery to reduce inflammation and cystoid macular oedema (CMO). Diclofenac 0.1% is used three to five times daily for 28 days and Bromfenac 0.09% twice daily for 14 days postoperatively. The...

Long-term effect of YAG LPI on corneal endothelium in PACS

This is a single-centre randomised controlled trial of 875 patients with bilateral primary angle closure suspect (PACS) who received YAG laser iridotomy (LPI) prophylactic treatment in one eye randomly and the fellow eye served as control over 72 months. Central...

Less extrusion of StopLoss Jones tubes

This is a retrospective comparison of the survival of StopLoss Jones tubes with conventional Lester Jones tubes. Between 2014 and 2016, 31 StopLoss and 59 Lester Jones tubes were inserted. The authors compared the extrusion and sinking-in rates between the...

An update on inherited retinal disorders (part 2): Approaches to therapy for IRDs

Part 1 of this topic can be found here There are currently no proven cures for inherited retinal disease (IRD). However, multiple avenues of research are being investigated to better understand disease mechanisms and trial potential therapies that may slow...