You searched for "Epithelial"

626 results found

The challenge of chorioretinal folds in virtual eye clinics

Chorioretinal or choroidal folds are parallel striations involving the retina, retinal pigment epithelium (RPE), Bruch’s membrane, and inner choroid [1]. They can arise from compressive stress on these layers, and their presence often serves as a diagnostic marker for underlying...

The paediatric cataract: an overview of the embryology and pathophysiology

In the first of the two articles (see Part 2 here) on paediatric cataracts, Samuel Aryee reviews the aetiology of this condition. Cataracts arise from opacification of the natural transparent lens, which can cause partial or total blindness. Although the...

Are retinal vein occlusions seasonal? And if so why might that be?

Some studies have reported a strong seasonal pattern to central retinal vein occlusion (CRVO) occurrence with a peak in January, but other studies have failed to replicate this finding. The authors sought to determine data for Stockholm’s seasonal variation in...

Intravitreal injection related endophthalmitis

This article reviews the incidence, clinical findings, risk factors, management and visual outcomes in intravitreal injection related endophthalmitis. Incidence of this complication is reported to be in the range of 0.038% to 0.065% (1 in 2000-3000 injections). Patients present typically...

Comparison of SIA from femtosecond laser and manual CCIs for cataract surgery

This study group compared the differences in surgically induced astigmatism (SIA) vector, flattening effect, torque and wound architecture following both femtosecond laser and manual clear corneal incisions (CCIs). A double-armed, randomised, prospective case series was conducted. Cataract surgery was performed...

Characteristics of limbal lymphatic vasculature on confocal microscopy

This ex vivo study aims to describe the morphological characteristics of the human limbal lymphatic vasculature using confocal microscopy and immunofluorescence. Twelve corneal specimens are obtained from human donor eyes. These corneal buttons are not suitable for transplantation due to...

Are corneal guttata an additional risk factor in complicated cataract surgery needing a future corneal transplant?

This registry-based cohort study from Sweden utilised data from the Swedish National Cataract Registry and the Swedish Cornea Transplant Registry. Patients who underwent phacoemulsification with a posterior intraocular lens between 2010 and 2012 numbered 192,476. Of these cases, 288 underwent...

Long-term effect of YAG LPI on corneal endothelium in PACS

This is a single-centre randomised controlled trial of 875 patients with bilateral primary angle closure suspect (PACS) who received YAG laser iridotomy (LPI) prophylactic treatment in one eye randomly and the fellow eye served as control over 72 months. Central...

G-CSF intravitreal injections for NAION: a pilot study

In rodent models with anterior ischemic optic neuropathy (AION), granulocyte colony-stimulating factor (G-CSF) confers a neuroprotective effect on retinal ganglion cells (RGCs) via anti-apoptotic and anti-inflammatory processes. This prospective study investigated the efficacy of intravitreal injection of G-CSF for the...

Feb/Mar 2018 Quiz

History A 48-year-old farmer with gradual worsening vision in her only eye was referred by her optician. She had recently moved to the UK and required an interpreter during consultation. She seemed to have had vision problems since childhood. Although...

Aug/Sep 2014 Quiz 1

History A 50-year-old female with a history of smoking, weight loss and cough presents to the ophthalmology clinic with a distorted pupil. Examination reveals a mass on the surface and within the iris (see Figure 1). The ophthalmologists decide to...

Dec/Jan 2019 Quiz

History A 72-year-old male presented to his GP with a large ulcerated lesion on his right lower eyelid present for six months and enlarging in size. He had an urgent referral to a tertiary centre for specialised examination. The lesion...