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Tear production levels and dry eye disease
Dry eye disease (DED) is multifactorial, caused by an alteration in the quality or quantity of tear film’s three layers. Several tests are available for diagnosis. The aim of this study was to determine if the Schirmer test (ST) could...The role of inflammation in the pathophysiology of DMO
Diabetic macular oedema (DMO) is a major cause of visual loss in diabetes, with a complex multifactorial pathogenesis. In the UK alone it is estimated that there are nearly 2.5 million diabetic patients aged over 12 years. Approximately 65,000 of...Diabetes and diabetic retinopathy: Changes in understanding of the disease over the last 25 years and how the UK is helping low-income countries tackle the challenges
Diabetes – a historical perspective Diabetes mellitus (DM) is a chronic disease caused by inherited and / or acquired deficiency in production of insulin by the pancreas, or by the ineffectiveness of the insulin produced. Such a deficiency results in...Do steroids prevent progression to proliferative diabetic retinopathy (PDR)?
There is continuing debate on the merits of pan-retinal photocoagulation (PRP) for severe pre-proliferative and proliferative DR versus the newer therapies that inhibit vascular endothelial growth factor (VEGF). This has been hotly debated [1] following the publication of findings from...The Real Top Gun: Professor Steve Schallhorn
Steve Schallhorn: Fighter Pilot. In the spring of 1987, I travelled to the cinema at Hendon Central in London with some school friends to watch the newly released movie The Witches of Eastwick starring Jack Nicholson and Michelle Pfeiffer. Unfortunately...What's trending Dec/Jan 2026
A round-up of the eye-related hot topics that have been trending on social media over the last few weeks. #SciFi #Vision Growing up at home, it was my job to read the crossword clues out to my parents. I usually...Investigating the link between corneal clarity and statin use
Transparency is a vital attribute of the cornea, necessary in preserving healthy vision. Maintaining this requires the collective input of the various layers of the cornea. Mostly, the layers implicated in this are the corneal stroma and endothelium [1]. Our...A guide to utilising your time efficiently to develop clinical and procedural skills as an aspiring ophthalmologist
Ophthalmology often receives limited coverage in the undergraduate medical curriculum, and the availability of foundation programme jobs in this field is also restricted, reducing exposure to this field for aspiring ophthalmologists. Even if you’re not planning to specialise in ophthalmology,...
Long-term effect of YAG LPI on corneal endothelium in PACS
This is a single-centre randomised controlled trial of 875 patients with bilateral primary angle closure suspect (PACS) who received YAG laser iridotomy (LPI) prophylactic treatment in one eye randomly and the fellow eye served as control over 72 months. Central...
Investigating the effect of signal strength on mean retinal nerve fibre layer
The aim of this study was to determine the effect of signal strength on mean retinal nerve fibre layer (RNFL) using spectralis optical coherence tomography (S-OCT). Thirty normal subjects were imaged with S-OCT using variably dense Bangerter foils to alter...
Impact of solar eclipses on vision
Solar retinopathy occurs as a result of mechanical and photochemical damage to the retina caused by exposure to excessive light. The authors presented the optical coherence tomography (OCT) and OCT-angiography findings of five patients who looked at the solar eclipse...
