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1584 results found

Brn3b neuroprotective effect in rat glaucoma model

An adeno-associated virus-directed overexpression of the Brn3b protein in hypothesised to confer neuroprotective effects in this paper. This is ultimately tested in a well-accepted rat glaucoma model (Morrison’s model: saline injection into episcleral veins of rat eyes with a force...

Episcleral brachytherapy (EB) for retinoblastoma (RB)

This retrospective study consisted of 11 eyes treated either with Iodine (I) -125 or Ruthenium (R) -106EB with a mean apical dose of 44Gy. There were five in group B (46%), three in group C (27%) and three in group...

Intermittent manual compression for CCF

Carotid cavernous fistulae (CCF) can be classified as high and low-flow or as having direct and indirect communication. Most commonly, management of high-flow CCF is with endovascular embolisation. The authors look at an alternative treatment for CCF in indirect low-flow...

MicroRNA inhibits corneal neovascularisation

MicroRNAs (miR) are small non-coding RNA that target mRNA for destruction. MiR target about 30% of the protein coding genes and fine tune their expression. MiR have been shown to be involved in several cellular processes including cell cycle, tissue...

Laser pointer maculopathy

The objective of this study was to describe the potential clinical presentations of retinal pathology resulting from exposure to laser pointers. The study included eight eyes of seven patients. Mean age was 18.7 years (12-36). Most were accidental self-inflicted while...

Switchover study from Botox to Xeomin for facial dystonia

This study carried out in the UK compared the clinical effectiveness and efficiency of switching patients from Botox® injections to Xeomin®. This was carried out in 20 essential blepharospasm, 12 hemifacial spasm and six aberrant facial nerve regeneration patients. Patients...

Can the angle of origin of the ophthalmic artery predict embolic trajectory?

A retrospective, comparative case-control study was used to test the hypothesis that a risk factor for retinal versus cerebral infarct is the angular origin of the ophthalmic artery from the internal carotid artery. The study compared one group (n=28) who...

Corneal hysteresis: An emerging biomarker in the management of glaucoma

Corneal hysteresis (CH) is gaining recognition as a valuable parameter in the management of glaucoma. Corneal hysteresis is defined as the difference between the inward and outward pressure responses of the cornea during deformation. This measurement reflects the viscoelastic properties...

Ultrasound imaging of the eyes

Since its initial use in the eyes fifty years ago, ultrasound has established itself as a common diagnostic technique in ophthalmology. Sonographers, engineers and clinicians from all around the world have contributed to the development of ocular ultrasonography. As a...

Will COVID-19 impact the selection of ophthalmology as a career choice by medical students?

The COVID-19 pandemic has had profound effects on medical education and has called for large shifts in the medical curriculum. Clinical attachments were suspended at the height of the pandemic and examinations were cancelled or were moved to an online...

A tarso-conjunctival flap for paralytic ectropion

This is a review of 110 patients with paralytic ectropion who underwent a lateral tarso-conjunctival flap procedure. The technique involves fashioning a 4-8mm wide lateral tarso-conjunctival flap in a similar way to a lateral Hughes flap. This is then sutured...

Webinar will look at impact of menopause on eye health

A BCLA webinar will look at the impact going through the menopause can have on female eye health.